Mirtrons: microRNA biogenesis via splicing
JO Westholm, EC Lai - Biochimie, 2011 - Elsevier
A well-defined mechanism governs the maturation of most microRNAs (miRNAs) in animals,
via stepwise cleavage of precursor hairpin transcripts by the Drosha and Dicer RNase III …
via stepwise cleavage of precursor hairpin transcripts by the Drosha and Dicer RNase III …
Biogenesis, characterization, and functions of mirtrons
U Salim, A Kumar, R Kulshreshtha… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
MicroRNAs (miRNAs) are major post‐transcriptional regulators of gene expression. They
base pair with the complementary target mRNA at the 3′ UTR and modulate cellular …
base pair with the complementary target mRNA at the 3′ UTR and modulate cellular …
Poly (A)-specific ribonuclease mediates 3′-end trimming of Argonaute2-cleaved precursor microRNAs
M Yoda, D Cifuentes, N Izumi, Y Sakaguchi, T Suzuki… - Cell reports, 2013 - cell.com
MicroRNAs (miRNAs) are typically generated as∼ 22-nucleotide double-stranded RNAs via
the processing of precursor hairpins by the ribonuclease III enzyme Dicer, after which they …
the processing of precursor hairpins by the ribonuclease III enzyme Dicer, after which they …
Transcriptome microRNA profiling of bovine mammary epithelial cells challenged with Escherichia coli or Staphylococcus aureusbacteria reveals pathogen directed …
Background MicroRNAs (miRNAs) can post-transcriptionally regulate gene expression and
have been shown to be critical regulators to the fine-tuning of epithelial immune responses …
have been shown to be critical regulators to the fine-tuning of epithelial immune responses …
Epigenetic marks: regulators of livestock phenotypes and conceivable sources of missing variation in livestock improvement programs
EM Ibeagha-Awemu, X Zhao - Frontiers in genetics, 2015 - frontiersin.org
Improvement in animal productivity has been achieved over the years through careful
breeding and selection programs. Today, variations in the genome are gaining increasing …
breeding and selection programs. Today, variations in the genome are gaining increasing …
MicroRNAome of porcine pre-and postnatal development
The domestic pig is of enormous agricultural significance and valuable models for many
human diseases. Information concerning the pig microRNAome (miRNAome) has been long …
human diseases. Information concerning the pig microRNAome (miRNAome) has been long …
Evolution of the let-7 microRNA family
The increase of bodyplan complexity in early bilaterian evolution is correlates with the
advent and diversification of microRNAs. These small RNAs guide animal development by …
advent and diversification of microRNAs. These small RNAs guide animal development by …
Dicer-independent, Ago2-mediated microRNA biogenesis in vertebrates
A canonical biogenesis pathway involving sequential cleavage by the Drosha and Dicer
RNAse III enzymes governs the maturation of most animal microRNAs. However, there exist …
RNAse III enzymes governs the maturation of most animal microRNAs. However, there exist …
Next generation sequencing reveals the expression of a unique miRNA profile in response to a gram-positive bacterial infection
MicroRNAs (miRNAs) are short, non-coding RNAs, which post-transcriptionally regulate
gene expression and are proposed to play a key role in the regulation of innate and …
gene expression and are proposed to play a key role in the regulation of innate and …
Mirtrons, an emerging class of atypical miRNA
HJ Curtis, CR Sibley, MJA Wood - Wiley Interdisciplinary …, 2012 - Wiley Online Library
Post‐transcriptional gene silencing (PTGS) via RNA interference (RNAi) is a vital gene
regulatory mechanism for fine‐tuning gene expression. RNAi effectors termed microRNAs …
regulatory mechanism for fine‐tuning gene expression. RNAi effectors termed microRNAs …