Gene transcription is a noisy process, and cell division cycle is an important source of gene
transcription noise. In this work, we develop a mathematical approach by coupling …

Gene transcription is a stochastic process, and is often activated by multiple signal
transduction pathways. In this work, we study gene transcription activated randomly by two …

Gene transcription is a central process in life. In single cells, it is a random process since
many regulatory molecules are present at low copy numbers. The randomness is best …

Randomness in gene transcription can result in fluctuations (noise) of messenger RNA
(mRNA) levels, leading to phenotypic plasticity in the isogenic populations of cells. Recent …

Life growth and development are driven by continuous cell divisions. Cell division is a
stochastic and complex process. In this paper, we study the impact of cell division on the …

Gene expression is the central process in cells, and is stochastic in nature. In this work, we
study the mean expression level of, and the expression noise in, a population of isogenic …

Gene transcription is a stochastic process, manifested by the heterogeneous mRNA
distribution in an isogenic cell population. Bimodal distribution has been observed in the …

The stochastic nature of cell-specific signal molecules (such as transcription factor,
ribosome, etc.) and the intrinsic stochastic nature of gene expression process result in cell-to …

Background: Gene transcription is a random bursting process that leads to large variability in
mRNA numbers in single cells. The main cause is largely attributed to random switching …

Gene transcription is a stochastic process, as the mRNA copies of the same gene in a
population of isogeneic cells are often distributed unevenly. The fluctuation has been …