Replacing in vivo with in vitro studies can increase sustainability in the development of
medicines. This principle has already been applied in the biowaiver approach based on the …

Phthalates are a class of compounds that have found widespread use in industrial
applications, in particular in the polymer, cosmetics and pharmaceutical industries. While …

In vitro diffusive models are an important tool to screen the penetration ability of active
ingredients in various formulations. A reliable assessment of skin penetration enhancing …

The objective of this study is to investigate the in vitro permeation of asiatic acid (AA) in the
form of a topical gel after entrapment in transfersomes by Franz diffusion cells …

New liposomes modified with pyrrolidinium surfactants containing a hydroxyethyl fragment
(C n PB, n= 12, 14, 16) were prepared for transdermal delivery of non-steroidal anti …

In the development and optimization of dermatological products, In Vitro Permeation Testing
(IVPT) is pivotal for controlled study of skin penetration. To enhance standardization and …

The aim of this study was to encapsulate cannabidiol (CBD) extract in nanostructured lipid
carriers (NLCs) to improve the chemical stability and anti-inflammatory activity of CBD for …

Topical administration of drug is an attractive alternative to the oral administration as it
provides a reduction in adverse reactions and an enhancement of therapeutic effects. The …

Unlike in many countries, in the USA, UV filters are treated as drugs and strictly regulated by
the Food and Drug Administration. So far, 17 physical and chemical sunscreen agents were …

This paper aimed to evaluate the effect of vehicle and chemical modifications of the structure
of active compounds on the skin permeation and accumulation of ibuprofen [IBU]. In vitro …