Sequencing pools of individuals—mining genome-wide polymorphism data without big funding

C Schlötterer, R Tobler, R Kofler, V Nolte - Nature Reviews Genetics, 2014 - nature.com
The analysis of polymorphism data is becoming increasingly important as a complementary
tool to classical genetic analyses. Nevertheless, despite plunging sequencing costs …

Genomic signatures of selection at linked sites: unifying the disparity among species

AD Cutter, BA Payseur - Nature Reviews Genetics, 2013 - nature.com
Population genetics theory supplies powerful predictions about how natural selection
interacts with genetic linkage to sculpt the genomic landscape of nucleotide polymorphism …

Why sex and recombination?

NH Barton, B Charlesworth - Science, 1998 - science.org
REVIEW Most higher organisms reproduce sexually, despite the automatic reproductive
advantage experienced by asexual variants. This implies the operation of selective forces …

Haplotype blocks and linkage disequilibrium in the human genome

JD Wall, JK Pritchard - Nature Reviews Genetics, 2003 - nature.com
There is great interest in the patterns and extent of linkage disequilibrium (LD) in humans
and other species. Characterizing LD is of central importance for gene-mapping studies and …

Genomic Variation in Natural Populations of Drosophila melanogaster

CH Langley, K Stevens, C Cardeno, YCG Lee… - Genetics, 2012 - academic.oup.com
This report of independent genome sequences of two natural populations of Drosophila
melanogaster (37 from North America and 6 from Africa) provides unique insight into forces …

Comparative recombination rates in the rat, mouse, and human genomes

MI Jensen-Seaman, TS Furey, BA Payseur… - Genome …, 2004 - genome.cshlp.org
Levels of recombination vary among species, among chromosomes within species, and
among regions within chromosomes in mammals. This heterogeneity may affect levels of …

Widespread Discordance of Gene Trees with Species Tree in Drosophila: Evidence for Incomplete Lineage Sorting

DA Pollard, VN Iyer, AM Moses, MB Eisen - PLoS genetics, 2006 - journals.plos.org
The phylogenetic relationship of the now fully sequenced species Drosophila erecta and D.
yakuba with respect to the D. melanogaster species complex has been a subject of …

Recombination and speciation

RK Butlin - Molecular ecology, 2005 - Wiley Online Library
Speciation can be viewed as the evolution of restrictions on the freedom of genetic
recombination: new combinations of alleles can be generated within species, but alleles …

The genomic distribution of transposable elements is driven by spatially variable purifying selection

AM Langmüller, V Nolte, M Dolezal… - Nucleic Acids …, 2023 - academic.oup.com
It is widely accepted that the genomic distribution of transposable elements (TEs) mainly
reflects the outcome of purifying selection and insertion bias. Nevertheless, the relative …

An evolutionary view of human recombination

G Coop, M Przeworski - Nature Reviews Genetics, 2007 - nature.com
Recombination has essential functions in mammalian meiosis, which impose several
constraints on the recombination process. However, recent studies have shown that, in spite …