Psychotic disorders affect 3% of the population at some stage in life, are a leading cause of
disability, and impose a great economic burden on society. Major breakthroughs in the …

Transcriptome-wide association studies (TWAS) goal is to better understand the etiology of
diseases and develop preventative and therapeutic approaches by examining the …

Trial-by-trial neural variability, a measure of neural response stability, has been examined in
relation to behavioral indicators using summary measures, but these methods do not …

Maternal immune activation (MIA) during prenatal development is an environmental risk
factor for psychiatric disorders including schizophrenia (SZ). Converging lines of evidence …

BackgroundDeficits in event-related potential (ERP) including duration mismatch negativity
(MMN) and P3a have been demonstrated widely in chronic schizophrenia (SZ) but …

Objective Auditory mismatch negativity (MMN) impairment is a candidate endophenotype in
psychotic disorders, yet the genetic underpinnings remain to be clarified. Here, we …

Psychosis and visual hallucinations are a prevalent non-motor symptom of Parkinson's
disease, negatively affecting patients' quality of life and constituting a greater risk for …

Abstract Background and Hypothesis Schizophrenia (SZ) and bipolar disorder (BD) share
genetic risk factors, yet patients display differential levels of cognitive impairment. We …

Abstract Background and Hypothesis Endophenotypes can help to bridge the gap between
psychosis and its genetic predispositions, but their underlying mechanisms remain largely …

Objective Canada exhibits one of highest lifetime prevalence for post-traumatic stress
disorder (PTSD), but the etiology of this debilitating mental health condition still remains …