To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

Extracellular vesicles set the stage for brain plasticity and recovery by multimodal signalling

DM Hermann, L Peruzzotti-Jametti, B Giebel… - Brain, 2024 - academic.oup.com
Extracellular vesicles (EVs) are extremely versatile naturally occurring membrane particles
that convey complex signals between cells. EVs of different cellular sources are capable of …

Methionine deprivation inhibits glioma proliferation and EMT via the TP53TG1/miR-96-5p/STK17B ceRNA pathway

J Li, R Liu, H Hu, Y Huang, Y Shi, H Li, H Chen… - npj Precision …, 2024 - nature.com
Recent research highlights the significant impact of methionine metabolism on glioma
progression. An increasing amount of compelling evidence bridges long non-coding RNAs …

The genetic algorithm-aided three-stage ensemble learning method identified a robust survival risk score in patients with glioma

S Zhu, W Kong, J Zhu, L Huang, S Wang… - Briefings in …, 2022 - academic.oup.com
Ensemble learning is a kind of machine learning method which can integrate multiple basic
learners together and achieve higher accuracy. Recently, single machine learning methods …

Advances in bioengineered CAR T/NK cell therapy for glioblastoma: Overcoming immunosuppression and nanotechnology‐based strategies for enhanced CAR T/NK …

N Dana, A Dabiri, MB Najafi, A Rahimi… - Bioengineering & …, 2024 - Wiley Online Library
Glioblastoma is a strong challenge in the worldwide field of central nervous system
malignancies. GBM's inherent heterogeneity, along with the formation of an …

[HTML][HTML] Glutamine-dependent effects of nitric oxide on cancer cells subjected to hypoxia-reoxygenation

D Xing, GA Benavides, MS Johnson, R Tian, S Barnes… - Nitric Oxide, 2023 - Elsevier
Limited O 2 availability can decrease essential processes in energy metabolism. However,
cancers have developed distinct metabolic adaptations to these conditions. For example …

[HTML][HTML] Choroid plexus tumors: a spectrum from benign to malignant

AA Mohamed, T Caussat, S Kelly, PM Johansen… - Tumor …, 2023 - accscience.com
Choroid plexus tumors (CPT) are believed to originate from outgrowths of the choroid
plexus. Despite their broad spectrum of symptoms, invasive nature, and prognosis, most …

Trends in metabolic signaling pathways of tumor drug resistance: A scientometric analysis

R Jiang, M Cao, S Mei, S Guo, W Zhang, N Ji… - Frontiers in …, 2022 - frontiersin.org
Background Cancer chemotherapy resistance is one of the most critical obstacles in cancer
therapy. Since Warburg O first observed alterations in cancer metabolism in the 1950s …

TIME is critical for oncolytic viral therapies against solid cancers

V Kumar, JH Stewart IV - 2024 - Springer
Cancer is a worldwide severe health issue, and its (colorectal and lung cancer) incidence is
increasing continuously in young adults. However, therapeutic advances have decreased …