Pathophysiology, diagnosis, prognosis, and prevention of poststroke epilepsy: clinical and research implications

T Tanaka, M Ihara, K Fukuma, NK Mishra, MJ Koepp… - Neurology, 2024 - AAN Enterprises
Poststroke epilepsy (PSE) is associated with higher mortality and poor functional and
cognitive outcomes in patients with stroke. With the remarkable development of acute stroke …

Insights into epileptogenesis from post-traumatic epilepsy

M Pease, K Gupta, SL Moshé, DJ Correa… - Nature Reviews …, 2024 - nature.com
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …

Polygenic risk of epilepsy and poststroke epilepsy

S Clocchiatti-Tuozzo, CA Rivier, S Misra, J Zelano… - Stroke, 2024 - ahajournals.org
BACKGROUND: Epilepsy is highly heritable, with numerous known genetic risk loci.
However, the genetic predisposition's role in poststroke epilepsy (PSE) remains …

Microenvironment‐Responsive Hydrogel Reduces Seizures After Traumatic Brain Injury in Juvenile Rats by Reducing Oxidative Stress and Hippocampal …

Z Han, Z Zhao, H Yu, L Wang, C Yue… - Macromolecular …, 2024 - Wiley Online Library
Traumatic brain injury (TBI) is the primary cause of child mortality and disability worldwide. It
can result in severe complications that significantly impact children's quality of life, including …

Association of serum uric acid levels with risk of epilepsy: A national population-based study

Y Wan, Q Kang, Y Wang, X Lu, J Li, H Nie, W Chai - Epilepsy & Behavior, 2024 - Elsevier
Background Uric acid (UA) serves as a crucial endogenous antioxidant in the body, offering
protection against oxidative stress, which may contribute to epilepsy pathogenesis. The …

Posttraumatic epilepsy in chronic disorders of consciousness due to severe traumatic brain injury after traffic accidents

S Yasuda, H Yano, Y Ikegame, M Kumagai… - … : European Journal of …, 2024 - Elsevier
Purpose To evaluate the clinical state of posttraumatic epilepsy (PTE) in patients with
chronic disorders of consciousness (CDC) due to severe traumatic brain injury (STBI) after …

Implications for driving based on the risk of seizures after ischaemic stroke

NK Mishra - Journal of Neurology, Neurosurgery & Psychiatry, 2024 - jnnp.bmj.com
Driving a motor vehicle is an important skill set. Its evaluation is relevant to patients who had
a stroke. These patients struggle to get back to driving because of physical deficits, including …

[引用][C] Activated protein C: A potential therapeutic target of post-stroke epileptogenesis

S Misra, NK Mishra - Epilepsy & Behavior, 2025 - Elsevier