Antitussive drugs—past, present, and future

PV Dicpinigaitis, AH Morice, SS Birring… - Pharmacological …, 2014 - ASPET
Cough remains a serious unmet clinical problem, both as a symptom of a range of other
conditions such as asthma, chronic obstructive pulmonary disease, gastroesophageal reflux …

[HTML][HTML] Intravenous lidocaine to prevent postoperative airway complications in adults: a systematic review and meta-analysis

SS Yang, NN Wang, T Postonogova, GJ Yang… - British journal of …, 2020 - Elsevier
Background In surgical patients undergoing general anaesthesia, coughing at the time of
extubation is common and can result in potentially dangerous complications. We performed …

Single‐dose dexmedetomidine attenuates airway and circulatory reflexes during extubation

G Guler, A Akin, Z Tosun, E Eskitascoglu… - Acta …, 2005 - Wiley Online Library
Background: The alpha agonist dexmedetomidine, a sedative and analgesic, reduces heart
rate and blood pressure dose‐dependently. We investigated whether it also has the ability to …

Lidocaine for preventing postoperative sore throat

Y Tanaka, T Nakayama, M Nishimori… - Cochrane database …, 2015 - cochranelibrary.com
Background Sore throat is a common side‐effect of general anaesthesia and is reported by
between 30% and 70% of patients after tracheal intubation. The likelihood of a sore throat …

Controlled comparison between betamethasone gel and lidocaine jelly applied over tracheal tube to reduce postoperative sore throat, cough, and hoarseness of voice

PA Sumathi, T Shenoy, M Ambareesha… - British journal of …, 2008 - academic.oup.com
Background Postoperative sore throat, cough, and hoarseness of voice though minor
sequelae after general tracheal anaesthesia can be distressing to the patient. Methods This …

Effect on postoperative sore throat of spraying the endotracheal tube cuff with benzydamine hydrochloride, 10% lidocaine, and 2% lidocaine

NK Hung, CT Wu, SM Chan, CH Lu… - Anesthesia & …, 2010 - journals.lww.com
BACKGROUND: Postoperative sore throat (POST) is a common complication after
endotracheal intubation. We compared the effectiveness on POST of spraying the …

Effect of intracuff lidocaine on postoperative sore throat and the emergence phenomenon: a systematic review and meta-analysis of randomized controlled trials

F Lam, YC Lin, HC Tsai, TL Chen, KW Tam, CY Chen - PLoS One, 2015 - journals.plos.org
Background Postoperative sore throat and other airway morbidities are common and
troublesome after endotracheal tube intubation general anesthesia (ETGA). We propose …

Comparison of the effects of dexmedetomidine versus fentanyl on airway reflexes and hemodynamic responses to tracheal extubation during rhinoplasty: A double …

R Aksu, A Akin, C Biçer, A Esmaoğlu, Z Tosun… - Current therapeutic …, 2009 - Elsevier
Background: Stimulation of various sites, from the nasal mucosa to the diaphragm, can
evoke laryngospasm. To reduce airway reflexes, tracheal extubation should be performed …

Alkalinization of intra‐cuff lidocaine and use of gel lubrication protect against tracheal tube‐induced emergence phenomena

JP Estebe, S Delahaye, P Le Corre… - British journal of …, 2004 - academic.oup.com
Background. We sought to determine the benefits of using alkalinized lidocaine 40 mg to fill
the cuff of a tracheal tube (ETT) in combination with water‐soluble gel lubrication to prevent …

Gargling with sodium azulene sulfonate reduces the postoperative sore throat after intubation of the trachea

J Ogata, K Minami, T Horishita, M Shiraishi… - Anesthesia & …, 2005 - journals.lww.com
IMPLICATIONS: Postoperative sore throat (POST) is a complication that remains to be
resolved in patients undergoing endotracheal intubation. In this study we found that …