Incretin peptides, principally GLP-1 and GIP, regulate islet hormone secretion, glucose
concentrations, lipid metabolism, gut motility, appetite and body weight, and immune …

Abstract Dipeptidyl peptidase-4 (DPP4) is a widely expressed enzyme transducing actions
through an anchored transmembrane molecule and a soluble circulating protein. Both …

The preproglucagon gene (Gcg) is expressed by specific enteroendocrine cells (L-cells) of
the intestinal mucosa, pancreatic islet α-cells, and a discrete set of neurons within the …

The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

The incretin effect, the amplification of insulin secretion occurring when glucose is taken in
orally as compared to infused intravenously, is one of the factors that help the body to …

Glucagon is secreted from islet α cells and controls blood levels of glucose in the fasting
state. Impaired glucagon secretion predisposes some patients with type 1 diabetes mellitus …

Textbook of Diabetes Classic textbook providing diabetologists and endocrinologists with
illustrated and clinically focused content on diabetes Now in its sixth edition, the Textbook of …

The intestine secretes a range of hormones with important local and distant actions,
including the control of insulin secretion and appetite. A number of enteroendocrine cell …

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)
are incretin hormones that control the secretion of insulin, glucagon, and somatostatin to …

Simple Summary When we ingest a meal, our intestine secretes hormones that are released
into the bloodstream. Amongst these hormones are the incretins hormones which stimulate …