[HTML][HTML] Natural products as chemo-radiation therapy sensitizers in cancers

S Nisar, T Masoodi, KS Prabhu, S Kuttikrishnan… - Biomedicine & …, 2022 - Elsevier
Cancer is a devastating disease and is the second leading cause of death worldwide.
Surgery, chemotherapy (CT), and/or radiation therapy (RT) are the treatment of choice for …

A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives

R Domitrović, I Potočnjak - Archives of toxicology, 2016 - Springer
Hepatoprotective effects of natural compounds have been frequently attributed to their
antioxidant properties and the ability to mobilize endogenous antioxidant defense system …

In Vitro and In Vivo Efficacy Studies of Lavender angustifolia Essential Oil and Its Active Constituents on the Proliferation of Human Prostate Cancer

Y Zhao, R Chen, Y Wang, C Qing… - Integrative cancer …, 2017 - journals.sagepub.com
Lavandula angustifolia is the most widely cultivated Lavandula species. The extraction of its
flower and leaves has been used as herbal medicine. In this study, the in vitro antitumor …

EGCG mediated targeting of deregulated signaling pathways and non-coding RNAs in different cancers: Focus on JAK/STAT, Wnt/β-Catenin, TGF/SMAD, NOTCH …

AA Farooqi, M Pinheiro, A Granja, F Farabegoli, S Reis… - Cancers, 2020 - mdpi.com
Decades of research have enabled us to develop a better and sharper understanding of
multifaceted nature of cancer. Next-generation sequencing technologies have leveraged our …

Anticarcinogenic effects of isothiocyanates on hepatocellular carcinoma

Y Zhang, H Huang, L Jin, S Lin - International Journal of Molecular …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer,
accounting for about 90% of cases. Sorafenib, lenvatinib, and the combination of …

In Vitro Toxicity of Epigallocatechin Gallate in Rat Liver Mitochondria and Hepatocytes

O Kucera, V Mezera, A Moravcova… - Oxidative Medicine …, 2015 - Wiley Online Library
Epigallocatechin‐3‐gallate (EGCG) is the main compound of green tea with well‐described
antioxidant, anti‐inflammatory, and tumor‐suppressing properties. However, EGCG at high …

[HTML][HTML] Green tea and black tea inhibit proliferation and migration of HepG2 cells via the PI3K/Akt and MMPs signalling pathway

L Sun, Y Zhang, W Zhang, X Lai, Q Li, L Zhang… - Biomedicine & …, 2020 - Elsevier
Background and aims Black tea and green tea were produced via different processing
techniques from the same tea leave variety. Then, biochemical components of the two water …

Down‐regulation of intracellular anti‐apoptotic proteins, particularly c‐FLIP by therapeutic agents; the novel view to overcome resistance to TRAIL

A Hassanzadeh, M Farshdousti Hagh… - Journal of cellular …, 2018 - Wiley Online Library
Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL or Apo2L) is a member of
the tumor necrosis factor (TNF) superfamily that induces apoptosis in different types of …

Novel investigations of flavonoids as chemopreventive agents for hepatocellular carcinoma

CY Liao, CC Lee, C Tsai, CW Hsueh… - BioMed research …, 2015 - Wiley Online Library
We would like to highlight the application of natural products to hepatocellular carcinoma
(HCC). We will focus on the natural products known as flavonoids, which target this disease …

Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway

X Shen, Y Zhang, Y Feng, L Zhang… - International …, 2014 - spandidos-publications.com
Abstract Epigallocatechin-3-gallate (EGCG) has been shown to inhibit the growth and
induce apoptosis of certain cancer cells. The aim of this study was to determine the role of …