Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Importance β-Lactam antibiotics are among the safest and most effective antibiotics. Many
patients report allergies to these drugs that limit their use, resulting in the use of broad …

Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

Background A reported penicillin allergy may compromise receipt of recommended
antibiotic prophylaxis intended to prevent surgical site infections (SSIs). Most patients with a …

Objective To evaluate the relation between penicillin allergy and development of meticillin
resistant Staphylococcus aureus (MRSA) and C difficile. Design Population based matched …

A recent survey of the European Academy of Allergy and Clinical Immunology (EAACI) Drug
Allergy Interest Group (DAIG) on how European allergy specialists deal with beta‐lactam …

Penicillin Allergy Many more patients are labeled as penicillin-allergic than actually are
allergic. The label should be analyzed with skin testing and test exposure. Patients with true …

Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …

The penicillin allergy label has been consistently linked with deleterious effects that span the
health care spectrum, including suboptimal clinical outcomes, the emergence of bacterial …

Drug hypersensitivity reactions (DHRs) to intravenous drugs can be severe and might leave
patients and doctors in a difficult position where an essential treatment or intervention has to …