Background Surgical stress can influence oncological outcome and survival. The enhanced
recovery after surgery (ERAS) protocol is designed to reduce perioperative stress and has …

Evidence suggests that excess perioperative activation of the sympathetic nervous system
and the consequent release of catecholamines (ie, epinephrine and norepinephrine) in the …

Circulating tumor DNA (ctDNA) has demonstrated great potential as a noninvasive
biomarker to assess minimal residual disease (MRD) and profile tumor genotypes in …

Aim: To summarize the literature on the long-term impact of perioperative opioids in
colorectal cancer. Materials & methods: Combined results from two searching strategies in …

Background Restricted perioperative fluid therapy is one of several interventions in the
enhanced recovery after surgery (ERAS) protocol, designed to reduce morbidity and …

Postoperative tumor microenvironments, such as cancer-associated adipocytes and
angiogenesis, severely affect the recurrence and metastasis of residual tumor cells …

Uncertainty regarding the development of postoperative metastatic disease is highly
prevalent. Here we assert that numerous processes that occur during the immediate …

Materials and Methods. To summarize the major challenges that cancer patients present for
the anaesthesiologists, a literature review was conducted. Articles presenting evidence or …

Background The surgical stress response (SSR) causes immunosuppression which may
cause residual tumor growth and micrometastasis after cancer surgery. We investigated …

German pathologist Otto Aichel suggested, a century ago, that the cancer cell acquired its
metastatic property from a leukocyte via cell-cell fusion. Since then, several revised versions …