Immunotherapy is a promising approach to treating various types of cancers, including
hepatocellular carcinoma (HCC). While single immunotherapy drugs show limited …

Epigenetics play a crucial role in gene regulation and cellular processes. Most importantly,
its dysregulation can contribute to the development of tumors. Epigenetic modifications, such …

Simple Summary Methyl-CpG binding protein 2 (MeCP2) is a nuclear protein that is mainly
studied for its role as an epigenetic regulator of gene transcription. Gene mutations affecting …

In precision oncology, therapy stratification is done based on the patients' tumor molecular
profile. Modeling and prediction of the drug response for a given tumor molecular type will …

The ultimate goal of cancer therapy is the elimination of disease from patients. Most directly,
this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a …

Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer, being the sixth
most commonly diagnosed cancer and the fourth leading cause of cancer-related death. As …

Introduction Multifocal lung adenocarcinoma (MFLA) is becoming increasingly recognized
as a distinct subset of lung cancer, with unique biology, disease course, and treatment …

Despite advances in diagnostic and therapeutic approaches for lung cancer, new therapies
targeting metastasis by the specific regulation of cancer genes are needed. In this study, we …

Simple Summary We thoroughly investigated the experimental and preclinical efficacy of the
novel hypomethylating agent (HMA) NTX-301 through comparative analyses with …

Hepatitis B virus (HBV) infection poses a challenge to global public health. Persistent liver
infection with HBV is associated with an increased risk of developing severe liver disease …