For over three decades, a mainstay and goal of clinical oncology has been the development
of therapies promoting the effective elimination of cancer cells by apoptosis. This …

Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

This review provides a comprehensive landscape of HGF/c-MET (hepatocyte growth factor
(HGF)/mesenchymal–epithelial transition factor (c-MET)) signaling pathway in cancers. First …

Activation of receptor tyrosine kinase (RTK) protein is frequently observed in malignant
progression of gliomas. In this study, the crosstalk activation of epidermal growth factor …

Primary effusion lymphoma (PEL) is a rare B-cell malignancy that most often occurs in
immunocompromised patients, such as HIV-infected individuals and patients receiving …

Background As one of the most common malignancy, lung adenocarcinoma (LUAD) is
characterized by low 5-year survival rate. This research aimed to investigate the effects of …

Liver diseases have consistently posed substantial challenges to global health. It is crucial
to find innovative methods to effectively prevent and treat these diseases. In recent times …

Hepatocyte growth factor (HGF) is a pleiotropic cytokine composed of an α-chain and a β-
chain, and these chains contain four kringle domains and a serine protease-like structure …

MET receptor has emerged as a druggable target across several human cancers. Agents
targeting MET and its ligand hepatocyte growth factor (HGF) including small molecules such …

Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of several human
cancers such as Kaposi's sarcoma (KS), which represents the most common AIDS …