Therapeutic advances in COVID-19

N Murakami, R Hayden, T Hills, H Al-Samkari… - Nature Reviews …, 2023 - nature.com
Over 2 years have passed since the start of the COVID-19 pandemic, which has claimed
millions of lives. Unlike the early days of the pandemic, when management decisions were …

Reporting of observational studies explicitly aiming to emulate randomized trials: a systematic review

HJ Hansford, AG Cashin, MD Jones… - JAMA network …, 2023 - jamanetwork.com
Importance Observational (nonexperimental) studies that aim to emulate a randomized trial
(ie, the target trial) are increasingly informing medical and policy decision-making, but it is …

Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients

T Langer, M Brioni, A Guzzardella, E Carlesso… - Critical Care, 2021 - Springer
Background Limited data are available on the use of prone position in intubated, invasively
ventilated patients with Coronavirus disease-19 (COVID-19). Aim of this study is to …

Effects of prone position on lung recruitment and ventilation-perfusion matching in patients with COVID-19 acute respiratory distress syndrome: a combined CT scan …

T Fossali, B Pavlovsky, D Ottolina, R Colombo… - Critical care …, 2022 - journals.lww.com
OBJECTIVES: Prone positioning allows to improve oxygenation and decrease mortality rate
in COVID-19–associated acute respiratory distress syndrome (C-ARDS). However, the …

Effect of prone versus supine position in COVID-19 patients: A systematic review and meta-analysis

EX Chua, SMISM Zahir, KT Ng, WY Teoh… - Journal of Clinical …, 2021 - Elsevier
Study objective To review the effects of prone position and supine position on oxygenation
parameters in patients with Coronavirus Disease 2019 (COVID-19). Design Systematic …

Early versus late awake prone positioning in non-intubated patients with COVID-19

R Kaur, DL Vines, S Mirza, A Elshafei, JA Jackson… - Critical Care, 2021 - Springer
Background Awake prone positioning (APP) is widely used in the management of patients
with coronavirus disease (COVID-19). The primary objective of this study was to compare …

Clinical trends among US adults hospitalized with COVID-19, March to December 2020: a cross-sectional study

S Garg, K Patel, H Pham, M Whitaker… - Annals of internal …, 2021 - acpjournals.org
Background: The COVID-19 pandemic has caused substantial morbidity and mortality.
Objective: To describe monthly clinical trends among adults hospitalized with COVID-19 …

Prone position in COVID 19-associated acute respiratory failure

A Kharat, M Simon, C Guérin - Current opinion in critical care, 2022 - journals.lww.com
Prone position in COVID 19-associated acute respiratory fail... : Current Opinion in Critical
Care Prone position in COVID 19-associated acute respiratory failure : Current Opinion in …

COVID-19 critical illness: a data-driven review

JC Ginestra, OJL Mitchell, GL Anesi… - Annual review of …, 2022 - annualreviews.org
The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges
in critical care medicine, including extreme demand for intensive care unit (ICU) resources …

Prone position in COVID-19 and-COVID-19 acute respiratory distress syndrome: an international multicenter observational comparative study

L Camporota, B Sanderson, D Chiumello… - Critical care …, 2022 - journals.lww.com
OBJECTIVES: Prone position is used in acute respiratory distress syndrome and in
coronavirus disease 2019 acute respiratory distress syndrome. However, it is unclear how …