The adverse childhood experiences questionnaire: Two decades of research on childhood trauma as a primary cause of adult mental illness, addiction, and medical …

EM Zarse, MR Neff, R Yoder, L Hulvershorn… - Cogent …, 2019 - Taylor & Francis
Abstract Objective. In 1998, Felitti and colleagues published the first study of the Adverse
Childhood Experiences-Questionnaire (ACE-Q), a 10-item scale used to correlate childhood …

Food for thought: how nutrition impacts cognition and emotion

SJ Spencer, A Korosi, S Layé, B Shukitt-Hale… - npj Science of …, 2017 - nature.com
More than one-third of American adults are obese and statistics are similar worldwide.
Caloric intake and diet composition have large and lasting effects on cognition and emotion …

The links between stress and depression: psychoneuroendocrinological, genetic, and environmental interactions

GE Tafet, CB Nemeroff - The Journal of neuropsychiatry and …, 2016 - Am Neuropsych Assoc
The role of stress in the origin and development of depression may be conceived as the
result of multiple converging factors, including the chronic effect of environmental stressors …

Chronic early life stress alters developmental and adult neurogenesis and impairs cognitive function in mice

EFG Naninck, L Hoeijmakers… - …, 2015 - Wiley Online Library
Early life stress (ES) increases vulnerability to psychopathology and impairs cognition in
adulthood. These ES‐induced deficits are associated with lasting changes in hippocampal …

Microbial 'Old Friends', immunoregulation and stress resilience

GAW Rook, CA Lowry, CL Raison - Evolution, medicine, and …, 2013 - academic.oup.com
Chronic inflammatory diseases (autoimmunity, allergy and inflammatory bowel diseases)
are increasing in prevalence in urban communities in high-income countries. One important …

Beneficial effects of environmental enrichment on behavior, stress reactivity and synaptophysin/BDNF expression in hippocampus following early life stress

Ε Dandi, A Kalamari, O Touloumi, R Lagoudaki… - International Journal of …, 2018 - Elsevier
Exposure to environmental enrichment can beneficially influence the behavior and enhance
synaptic plasticity. The aim of the present study was to investigate the mediated effects of …

Hippocampus, amygdala, and thalamus volumes in very preterm children at 8 years: neonatal pain and genetic variation

CMY Chau, M Ranger, M Bichin, MTM Park… - Frontiers in Behavioral …, 2019 - frontiersin.org
Altered hippocampal morphology and reduced volumes have been found in children born
preterm compared to full-term. Stress inhibits neurogenesis in the hippocampus, and …

Interpreting stress responses during routine toxicity studies: a review of the biology, impact, and assessment

NE Everds, PW Snyder, KL Bailey… - Toxicologic …, 2013 - journals.sagepub.com
Stress often occurs during toxicity studies. The perception of sensory stimuli as stressful
primarily results in catecholamine release and activation of the hypothalamic–pituitary …

[HTML][HTML] Adult neurogenesis, human after all (again): Classic, optimized, and future approaches

PJ Lucassen, CP Fitzsimons, E Salta… - Behavioural brain …, 2020 - Elsevier
In this perspective article, we reflect on the recent debate about the existence of human
neurogenesis and discuss direct, and also indirect, support for the ongoing formation, and …

Perinatal programming of adult hippocampal structure and function; emerging roles of stress, nutrition and epigenetics

PJ Lucassen, EFG Naninck, JB van Goudoever… - Trends in …, 2013 - cell.com
Early-life stress lastingly affects adult cognition and increases vulnerability to
psychopathology, but the underlying mechanisms remain elusive. In this Opinion article, we …