[HTML][HTML] SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies
Monoclonal antibodies (mAbs) offer a treatment option for individuals with severe COVID-19
and are especially important in high-risk individuals where vaccination is not an option …
and are especially important in high-risk individuals where vaccination is not an option …
Omicron: what makes the latest SARS-CoV-2 variant of concern so concerning?
Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …
[HTML][HTML] Considerable escape of SARS-CoV-2 Omicron to antibody neutralization
D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant was first identified in November 2021 in
Botswana and South Africa,–. It has since spread to many countries and is expected to …
Botswana and South Africa,–. It has since spread to many countries and is expected to …
[HTML][HTML] Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization
D Planas, D Veyer, A Baidaliuk, I Staropoli… - Nature, 2021 - nature.com
Abstract The SARS-CoV-2 B. 1.617 lineage was identified in October 2020 in India,,,–. Since
then, it has become dominant in some regions of India and in the UK, and has spread to …
then, it has become dominant in some regions of India and in the UK, and has spread to …
[HTML][HTML] SARS-CoV-2 501Y. V2 escapes neutralization by South African COVID-19 donor plasma
Abstract SARS-CoV-2 501Y. V2 (B. 1.351), a novel lineage of coronavirus causing COVID-
19, contains substitutions in two immunodominant domains of the spike protein. Here, we …
19, contains substitutions in two immunodominant domains of the spike protein. Here, we …
[HTML][HTML] Understanding the role of SARS-CoV-2 ORF3a in viral pathogenesis and COVID-19
J Zhang, A Ejikemeuwa, V Gerzanich, M Nasr… - Frontiers in …, 2022 - frontiersin.org
The ongoing SARS-CoV-2 pandemic has shocked the world due to its persistence, COVID-
19-related morbidity and mortality, and the high mutability of the virus. One of the major …
19-related morbidity and mortality, and the high mutability of the virus. One of the major …
[HTML][HTML] Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain
The continual evolution of SARS-CoV-2 and the emergence of variants that show resistance
to vaccines and neutralizing antibodies threaten to prolong the COVID-19 pandemic …
to vaccines and neutralizing antibodies threaten to prolong the COVID-19 pandemic …
[HTML][HTML] Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …
burden to the global society and is accompanied by various evolution of the virus genome …
[HTML][HTML] Current status of therapeutic monoclonal antibodies against SARS-CoV-2
S Kumar, A Chandele, A Sharma - PLoS pathogens, 2021 - journals.plos.org
The ongoing Coronavirus Disease 2019 (COVID-19) pandemic has taken a toll on millions
of lives worldwide. Currently, India has the second highest number of active COVID-19 …
of lives worldwide. Currently, India has the second highest number of active COVID-19 …
[HTML][HTML] Coronavirus Resistance Database (CoV-RDB): SARS-CoV-2 susceptibility to monoclonal antibodies, convalescent plasma, and plasma from vaccinated …
As novel SARS-CoV-2 variants with different patterns of spike protein mutations have
emerged, the susceptibility of these variants to neutralization by antibodies has been rapidly …
emerged, the susceptibility of these variants to neutralization by antibodies has been rapidly …