JAK-STAT signaling: a double-edged sword of immune regulation and cancer progression

KL Owen, NK Brockwell, BS Parker - Cancers, 2019 - mdpi.com
Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling mediates
almost all immune regulatory processes, including those that are involved in tumor cell …

[HTML][HTML] Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential

YS Fu, TH Chen, L Weng, L Huang, D Lai… - Biomedicine & …, 2021 - Elsevier
Curcumin, isolated from Curcuma longa L., is a fat-soluble natural compound that can be
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …

Curcumin and colorectal cancer: An update and current perspective on this natural medicine

W Weng, A Goel - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of most common malignancies worldwide and its incidence
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …

Pathogenic role of exosomes and microRNAs in HPV‐mediated inflammation and cervical cancer: a review

J Sadri Nahand, M Moghoofei… - … journal of cancer, 2020 - Wiley Online Library
Cervical cancer (CC) is the fourth most common cause of cancer death in women. The most
important risk factor for the development of CC is cervical infection with human papilloma …

Curcumin in cancer therapy: A novel adjunct for combination chemotherapy with paclitaxel and alleviation of its adverse effects

M Ashrafizadeh, A Zarrabi, F Hashemi, ER Moghadam… - Life sciences, 2020 - Elsevier
Dealing with cancer is of importance due to enhanced incidence rate of this life-threatening
disorder. Chemotherapy is an ideal candidate in overcoming and eradication of cancer. To …

Platinum nanoparticles in biomedicine: Preparation, anti-cancer activity, and drug delivery vehicles

A Abed, M Derakhshan, M Karimi… - Frontiers in …, 2022 - frontiersin.org
Cancer is the main cause of morbidity and mortality worldwide, excluding infectious disease.
Because of their lack of specificity in chemotherapy agents are used for cancer treatment …

[HTML][HTML] Polysaccharide-based nanomedicines for cancer immunotherapy: A review

Y Zeng, Y Xiang, R Sheng, H Tomás, J Rodrigues… - Bioactive Materials, 2021 - Elsevier
Cancer immunotherapy is an effective antitumor approach through activating immune
systems to eradicate tumors by immunotherapeutics. However, direct administration of …

A novel combination of vitamin C, curcumin and glycyrrhizic acid potentially regulates immune and inflammatory response associated with coronavirus infections: a …

L Chen, C Hu, M Hood, X Zhang, L Zhang, J Kan, J Du - Nutrients, 2020 - mdpi.com
Novel coronaviruses (CoV) have emerged periodically around the world in recent years. The
recurrent spreading of CoVs imposes an ongoing threat to global health and the economy …

Curcumin reinforces MSC‐derived exosomes in attenuating osteoarthritis via modulating the miR‐124/NF‐kB and miR‐143/ROCK1/TLR9 signalling pathways

B Qiu, X Xu, P Yi, Y Hao - Journal of Cellular and Molecular …, 2020 - Wiley Online Library
Curcumin treatment was reported to delay the progression of OA, but its underlying
mechanism remains unclear. In this study, we aimed to investigate the molecular …

[HTML][HTML] Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer

M Fallah, A Davoodvandi, S Nikmanzar, S Aghili… - Biomedicine & …, 2021 - Elsevier
Silymarin contains a group of closely-related flavonolignan compounds including silibinin,
and is extracted from Silybum marianum species, also called milk thistle. Silymarin has been …