Early-stage triple-negative breast cancer journey: beginning, end, and everything in between

HS Han, P Vikas, RLB Costa, N Jahan… - American Society of …, 2023 - ascopubs.org
Triple-negative breast cancer (TNBC) is a very heterogeneous and aggressive breast
cancer subtype with a high risk of mortality, even if diagnosed early. The mainstay of early …

Neoadjuvant Therapy: Current Landscape and Future Horizons for ER-Positive/HER2-Negative and Triple-Negative Early Breast Cancer

H Bischoff, M Espié, T Petit - Current Treatment Options in Oncology, 2024 - Springer
Opinion Statement Navigating the complex landscape of breast cancer treatment involves
distinct strategies for luminal and triple-negative subtypes. While neoadjuvant chemotherapy …

Long-term outcomes of neoadjuvant immunotherapy plus chemotherapy in patients with early-stage triple-negative breast cancer: an extracted individual patient data …

MT Cunha, MC Gouveia, FL Neto, L Testa… - British Journal of …, 2024 - nature.com
Background Neoadjuvant immunotherapy (nIO) has emerged as a treatment option for stage
II–III triple-negative breast cancer (TNBC). While randomised clinical trials (RCTs) …

Progress in immune checkpoint inhibition in early-stage triple-negative breast cancer

A Mohamed, M Kruse, J Tran - Expert Review of Anticancer …, 2023 - Taylor & Francis
Introduction Immune checkpoint inhibitors have been particularly effective in treating
cancers with robust immune microenvironments and have been successfully incorporated …

[HTML][HTML] Shifting the Paradigm: The Transformative Role of Neoadjuvant Therapy in Early Breast Cancer

N Hirmas, J Holtschmidt, S Loibl - Cancers, 2024 - mdpi.com
Simple Summary Neoadjuvant therapy, used before surgery, is an important part of breast
cancer treatment. Not only can it shrink tumors, but it can also provide valuable information …

Platinum‐based chemotherapy for early triple‐negative breast cancer

SRE Mason, ML Willson, SJ Egger… - Cochrane Database …, 2023 - cochranelibrary.com
Background Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast
cancer associated with shorter survival and a higher likelihood of the cancer returning. In …

Tailoring neoadjuvant systemic therapy in breast cancer:“The advent of a personalized approach”—The Breast‐Gynecological and Immuno‐Oncology International …

H Elghazaly, HA Azim, HS Rugo, D Cameron… - Cancer, 2024 - Wiley Online Library
Background The management of early breast cancer (BC) has witnessed an uprise in the
use of neoadjuvant therapy and a remarkable reshaping of the systemic therapy …

[HTML][HTML] По следам SABCS 2022: TOP-16 исследований по раннему раку молочной железы, которые могут изменить нашу клиническую практику

ИВ Колядина - Современная онкология, 2023 - cyberleninka.ru
Проведен анализ исследований, представленных на конференции SABCS 2022 по
лечению рака молочной железы (РМЖ); выделены 16 наиболее интересных и …

Neoadjuvant carboplatin in triple-negative breast cancer: results from NACATRINE, a randomized phase II clinical trial

C de Pádua Souza, ASB Carneiro… - Breast Cancer Research …, 2023 - Springer
Background Neoadjuvant chemotherapy (NACT) is the mainstay of treatment of stages II and
III triple-negative breast cancer (TNBC). This study aims to evaluate if the addition of …

A Narrative Review of the Clinical, Humanistic, and Economic Value of Pembrolizumab-Based Immunotherapy for the Treatment of Breast and Gynecologic Cancers

MJ Monberg, S Keefe, V Karantza, K Tryfonidis… - Oncology and …, 2024 - Springer
Breast and gynecologic cancers are common across the world and are associated with
substantial societal and economic burden. Pembrolizumab was among the first immune …