Pathophysiology of atherosclerosis

S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Effect of Freeze‐Drying on Apple Pomace and Pomegranate Peel Powders Used as a Source of Bioactive Ingredients for the Development of Functional Yogurt

M Ahmed, A Ali, A Sarfraz, Q Hong… - Journal of Food …, 2022 - Wiley Online Library
Agro‐industrial by‐products of fruits have turned into an essential source of bioactive
products. This study examined the effect of freeze‐drying on apple pomace powder (APP) …

CARMN Is an Evolutionarily Conserved Smooth Muscle Cell–Specific LncRNA That Maintains Contractile Phenotype by Binding Myocardin

K Dong, J Shen, X He, G Hu, L Wang, I Osman… - Circulation, 2021 - Am Heart Assoc
Background: Vascular homeostasis is maintained by the differentiated phenotype of
vascular smooth muscle cells (VSMCs). The landscape of protein coding genes comprising …

[HTML][HTML] Targeting smooth muscle cell phenotypic switching in vascular disease

R Chakraborty, P Chatterjee, JM Dave, AC Ostriker… - JVS-vascular …, 2021 - Elsevier
Objective The phenotypic plasticity of vascular smooth muscle cells (VSMCs) is central to
vessel growth and remodeling, but also contributes to cardiovascular pathologies. New …

miR-22 is a novel mediator of vascular smooth muscle cell phenotypic modulation and neointima formation

F Yang, Q Chen, S He, M Yang, EM Maguire, W An… - Circulation, 2018 - Am Heart Assoc
Background: MicroRNA-22 (miR-22) has recently been reported to play a regulatory role
during vascular smooth muscle cell (VSMC) differentiation from stem cells, but little is known …

Long noncoding RNA NEAT1 (nuclear paraspeckle assembly transcript 1) is critical for phenotypic switching of vascular smooth muscle cells

ASI Ahmed, K Dong, J Liu, T Wen… - Proceedings of the …, 2018 - National Acad Sciences
In response to vascular injury, vascular smooth muscle cells (VSMCs) may switch from a
contractile to a proliferative phenotype thereby contributing to neointima formation. Previous …

MicroRNAs in the pathobiology and therapy of atherosclerosis

B Laffont, KJ Rayner - Canadian Journal of Cardiology, 2017 - Elsevier
MicroRNAs are short noncoding RNAs, expressed in humans and involved in sequence-
specific post-transcriptional regulation of gene expression. They have emerged as key …

MicroRNA regulation of phenotypic transformations in vascular smooth muscle: relevance to vascular remodeling

G Wang, Y Luo, X Gao, Y Liang, F Yang, J Wu… - Cellular and Molecular …, 2023 - Springer
Alterations in the vascular smooth muscle cells (VSMC) phenotype play a critical role in the
pathogenesis of several cardiovascular diseases, including hypertension, atherosclerosis …

Non‐coding RNAs to treat vascular smooth muscle cell dysfunction

SD Brown, E Klimi, WAM Bakker… - British Journal of …, 2025 - Wiley Online Library
Vascular smooth muscle cell (vSMC) dysfunction is a critical contributor to cardiovascular
diseases, including atherosclerosis, restenosis and vein graft failure. Recent advances have …

The role of Hippo/yes‐associated protein signalling in vascular remodelling associated with cardiovascular disease

J He, Q Bao, M Yan, J Liang, Y Zhu… - British journal of …, 2018 - Wiley Online Library
Vascular remodelling is a vital process of a wide range of cardiovascular diseases and
represents the altered structure and arrangement of blood vessels. The Hippo pathway …