Inhalation drug delivery devices: technology update

M Ibrahim, R Verma… - … Devices: Evidence and …, 2015 - Taylor & Francis
The pulmonary route of administration has proven to be effective in local and systemic
delivery of miscellaneous drugs and biopharmaceuticals to treat pulmonary and non …

Inhaled liposomal antimicrobial delivery in lung infections

M Bassetti, A Vena, A Russo, M Peghin - Drugs, 2020 - Springer
The management of difficult-to-treat acute and chronic respiratory infections (infections in
cystic fibrosis, non-cystic fibrosis bronchiectasis, immunocompromised and mechanically …

Nebulizers for drug delivery to the lungs

AR Martin, WH Finlay - Expert opinion on drug delivery, 2015 - Taylor & Francis
Introduction: Nebulizers are the oldest modern method of delivering aerosols to the lungs for
the purpose of respiratory drug delivery. While use of nebulizers remains widespread in the …

The function and performance of aqueous aerosol devices for inhalation therapy

TC Carvalho, JT McConville - Journal of Pharmacy and …, 2016 - academic.oup.com
Objectives In this review paper, we explore the interaction between the functioning
mechanism of different nebulizers and the physicochemical properties of the formulations for …

Natural sources and experimental generation of bioaerosols: challenges and perspectives

M Alsved, L Bourouiba, C Duchaine… - Aerosol Science and …, 2020 - Taylor & Francis
Experimental aerosol generation methods aim to represent natural processes; however, the
complexity is not always captured and unforeseen variability may be introduced into the …

Liposomes for pulmonary drug delivery: the role of formulation and inhalation device design

A Elhissi - Current pharmaceutical design, 2017 - ingentaconnect.com
Liposomes are established drug carriers for inhalation owing to their safety and ability to
provide controlled drug release in the lung. These carriers can entrap a wide range of …

Simultaneous pulmonary administration of celecoxib and naringin using a nebulization-friendly nanoemulsion: A device-targeted delivery for treatment of lung cancer

R Said-Elbahr, M Nasr, MA Alhnan, I Taha… - Expert opinion on …, 2022 - Taylor & Francis
Background Lung cancer is a principal cause of death worldwide, and its treatment is very
challenging. Nebulization offers a promising means of targeting drugs to their site of action …

Nebulizable colloidal nanoparticles co-encapsulating a COX-2 inhibitor and a herbal compound for treatment of lung cancer

R Said-Elbahr, M Nasr, MA Alhnan, I Taha… - European journal of …, 2016 - Elsevier
A challenging disease such as lung cancer requires the combination of different modalities
to achieve beneficial therapeutic outcomes. In this work, PLGA nanoparticles were chosen …

Not all nebulizers are created equal: Considerations in choosing a nebulizer for aerosol delivery during mechanical ventilation

R MacLoughlin, I Martin-Loeches - Expert Review of Respiratory …, 2023 - Taylor & Francis
Introduction Aerosol therapy is commonly prescribed in the mechanically ventilated patient.
Jet nebulizers (JN) and vibrating mesh nebulizers (VMN) are the most common nebulizer …

Advances in device and formulation technologies for pulmonary drug delivery

JGY Chan, J Wong, QT Zhou, SSY Leung, HK Chan - Aaps Pharmscitech, 2014 - Springer
Inhaled pharmaceuticals are formulated and delivered differently according to the
therapeutic indication. However, specific device-formulation coupling is often fickle, and new …