The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra

MC Vogg, J Ferenc, WC Buzgariu, C Perruchoud… - Science …, 2022 - science.org
The molecular mechanisms that maintain cellular identities and prevent dedifferentiation or
transdifferentiation remain mysterious. However, both processes are transiently used during …

High Intrinsic Oncogenic Potential in the Myc-Box-Deficient Hydra Myc3 Protein

M Lechable, X Tang, S Siebert, A Feldbacher… - Cells, 2023 - mdpi.com
The proto-oncogene myc has been intensively studied primarily in vertebrate cell culture
systems. Myc transcription factors control fundamental cellular processes such as cell …