Mycobacterial signaling through toll-like receptors

J Basu, DM Shin, EK Jo - Frontiers in cellular and infection …, 2012 - frontiersin.org
Studies over the past decade have helped to decipher molecular networks dependent on
Toll-like receptor (TLR) signaling, in mycobacteria-infected macrophages. Stimulation of …

Autoimmune disease in the era of the metagenome

AD Proal, PJ Albert, T Marshall - Autoimmunity Reviews, 2009 - Elsevier
Studies of autoimmune disease have focused on the characteristics of the identifiable
antibodies. But as our knowledge of the genes associated with the disease states expands …

Evaluation of tumor necrosis factor (TNF)-α mRNA expression level and the rs1799964 polymorphism of the TNF-α gene in peripheral mononuclear cells of patients …

M Nourian, V Chaleshi, L Pishkar… - Biomedical …, 2017 - spandidos-publications.com
Crohn's disease (CD) and ulcerative colitis (UC) are types of chronic inflammatory bowel
disease (IBD) of which the actual causes remain unknown. Emerging data indicate that …

An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice

A Khan, P Bakhru, S Saikolappan, K Das, E Soudani… - npj Vaccines, 2019 - nature.com
Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis due to M.
tuberculosis (Mtb), which kills millions of people each year. BCG variably protects children …

Spatiotemporal patterns and ecological factors of tuberculosis notification: A spatial panel data analysis in Guangxi, China

Z Cui, D Lin, V Chongsuvivatwong, J Zhao, M Lin… - PLoS …, 2019 - journals.plos.org
Background Guangxi is one of the provinces having the highest notification rate of
tuberculosis in China. However, spatial and temporal patterns and the association between …

Association between vitamin D receptor polymorphisms and periodontitis: A meta‐analysis

L Chen, H Li, P Zhang, S Wang - Journal of periodontology, 2012 - Wiley Online Library
Background: The purpose of the meta‐analysis is to explore the association between
vitamin D receptor polymorphisms (including four gene loci: Taq‐I, Bsm‐I, Apa‐I, and Fok‐I) …

Cytokine genes are associated with tuberculin skin test response in a native Brazilian population

VM Zembrzuski, PC Basta, SM Callegari-Jacques… - Tuberculosis, 2010 - Elsevier
Tuberculosis was a major cause of population decline among Brazilian indigenous peoples
and remains a leading cause of morbidity and mortality among them. Despite high BCG …

[HTML][HTML] Inflammatory disease and the human microbiome

AD Proal, PJ Albert, TG Marshall - Discovery medicine, 2014 - discoverymedicine.com
The human body is a superorganism in which thousands of microbial genomes continually
interact with the human genome. A range of physical and neurological inflammatory …

A reappraised meta-analysis of the genetic association between vitamin D receptor BsmI (rs1544410) polymorphism and pulmonary tuberculosis risk

MY Areeshi, RK Mandal, SA Dar… - Bioscience …, 2017 - portlandpress.com
Bsm I (rs1544410) polymorphism located in intron 8 at the 3′-end of the vitamin D receptor
(VDR) gene is known to be involved in the regulation of mRNA stability. Many studies …

P2X7 gene polymorphisms and risk assessment for pulmonary tuberculosis in Asian Indians

V Sambasivan, KJR Murthy, R Reddy… - Disease …, 2010 - Wiley Online Library
Objective: Pulmonary tuberculosis (PTB) is a leading cause of morbidity and mortality.
Macrophages play an important role in the immunopathogenesis of tuberculosis …