Esophageal motility disorders are prevalent in 90% of patients with systemic sclerosis
[scleroderma (SSc)], with an increased mortality rate in patients with severe esophageal …

The gastrointestinal tract (GI) is the second most affected organ system in individuals
suffering from systemic/localized scleroderma (SSc) or localized scleroderma. SSc can affect …

Systemic sclerosis is an autoimmune disease characterized by vascular disease, fibrosis of
the skin, and internal organ dysfunction. Gastrointestinal involvement is the most frequent …

Systemic sclerosis (SSc) is a rare autoimmune disease of the connective tissue that can
affect multiple organs. The esophagus is the most affected gastrointestinal tract, while …

The esophagus is the most commonly affected part of the gastrointestinal system in patients
with systemic sclerosis (SSc). Esophageal involvement may lead to a significant reduction in …

High resolution manometry (HRM), developed from conventional manometry, is the gold
standard for assessment of esophageal motor function worldwide. The Chicago …

Absent contractility (AC), a motility disorder characterized by the absence of esophageal
contractions while maintaining normal lower esophageal sphincter relaxation, is recognized …

(1) Background: Absent contractility (AC) is an esophageal motility disorder defined as a
normal integrated relaxation pressure with 100% failed peristalsis. We sought to clarify the …

Objective To assess whether patient and physician global assessment of gastrointestinal
tract (GIT) disease in systemic sclerosis (SSc) are associated with a meaningful change in …

Esophageal manometry is a valuable tool for the evaluation of dysphagia, as most
esophageal motility disorders may cause this symptom. High-resolution manometry is used …