“Bet hedging” against climate change in developing and adult animals: roles for stochastic gene expression, phenotypic plasticity, epigenetic inheritance and …

WW Burggren, JF Mendez-Sanchez - Frontiers in Physiology, 2023 - frontiersin.org
Animals from embryos to adults experiencing stress from climate change have numerous
mechanisms available for enhancing their long-term survival. In this review we consider …

Experimental upregulation of developmentally downregulated ribosomal protein large subunits 7 and 7A promotes axon regeneration after injury in vivo

J Xing, WC Theune, A Lukomska, MP Frost… - Experimental …, 2023 - Elsevier
Ribosomal proteins are involved in neurodevelopment and central nervous system (CNS)
disease and injury. However, the roles of specific ribosomal protein subunits in …

[HTML][HTML] Decoding the molecular script of 2′-O-ribomethylation: Implications across CNS disorders

AK Verma, B Roy, Y Dwivedi - Heliyon, 2024 - cell.com
Emerging evidence underscores the critical role of impaired mRNA translation in various
neurobiological conditions. Ribosomal RNA (rRNA), essential for protein synthesis …

Quantitative Proteomics Characterization of the Effect and Mechanism of Trichostatin A on the Hippocampus of Type II Diabetic Mice

W Wei, Q Zhang, T Jin, L Zhu, J Zhao, F Li… - Cellular and Molecular …, 2023 - Springer
Diabetic encephalopathy (DE) is one of the complications of diabetes mellitus with mild-to-
moderate cognitive impairment. Trichostatin A (TSA) has been revealed to show protective …

Raphe and ventrolateral medulla proteomics in sudden unexplained death in childhood with febrile seizure history

DF Leitner, C William, A Faustin, E Kanshin… - Acta …, 2024 - Springer
Sudden unexplained death in childhood (SUDC) is death of a child≥ 12 months old that is
unexplained after autopsy and detailed analyses. Among SUDC cases,~ 30% have febrile …

Neurodegenerative diseases reflect the reciprocal roles played by retroelements in regulating memory and immunity

A Herbert - Frontiers in Neuroscience, 2024 - frontiersin.org
Tetrapod endogenous retroelements (ERE) encode proteins that have been exapted to
perform many roles in development and also in innate immunity, including GAG (group …

[HTML][HTML] CCN1 derived from vascular endothelial cells impairs cognitive function in Alzheimer's disease model mice

S Hirabayashi, A Uyeda, I Manabe, Y Yonezu… - Journal of …, 2025 - Elsevier
Vascular endothelial cell-expressing molecules regulate neuronal function. Although
cerebrovascular dysregulation is a hallmark of Alzheimer's disease (AD), the effect of …

Low-dose exposure to malathion and radiation results in the dysregulation of multiple neuronal processes, inducing neurotoxicity and neurodegeneration in mouse

RK Narasimhamurthy, BS Venkidesh, S Nayak… - … Science and Pollution …, 2024 - Springer
Neurodegenerative disorders are a debilitating and persistent threat to the global elderly
population, carrying grim outcomes. Their genesis is often multifactorial, with a history of …

Short-term and long-term sensitization differentially alters the composition of an anterograde transport complex in Aplysia

A Sadhu, KK Badal, Y Zhao, AA Ali, S Swarnkar… - eneuro, 2023 - eneuro.org
Long-term memory formation requires anterograde transport of proteins from the soma of a
neuron to its distal synaptic terminals. This allows new synaptic connections to be grown …

Sex-specific transcriptional signatures in the medial prefrontal cortex underlying sexually dimorphic behavioural responses to stress in rats

YD Zhang, DD Shi, S Zhang, Z Wang - Journal of Psychiatry and …, 2023 - jpn.ca
Background: Converging evidence suggests that stress alters behavioural responses in a
sex-specific manner; however, the underlying molecular mechanisms of stress remain …