Genetic load: genomic estimates and applications in non-model animals
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …
the mean fitness of a population, both now and in the future. This 'genetic load'has been …
[HTML][HTML] Deleterious variation in natural populations and implications for conservation genetics
Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …
that many organisms face ongoing threats of extinction, there is interest in elucidating the …
The inflated significance of neutral genetic diversity in conservation genetics
JC Teixeira, CD Huber - Proceedings of the National …, 2021 - National Acad Sciences
The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …
[HTML][HTML] 863 genomes reveal the origin and domestication of chicken
Despite the substantial role that chickens have played in human societies across the world,
both the geographic and temporal origins of their domestication remain controversial. To …
both the geographic and temporal origins of their domestication remain controversial. To …
[HTML][HTML] Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology
J Plassais, J Kim, BW Davis, DM Karyadi… - Nature …, 2019 - nature.com
Domestic dog breeds are characterized by an unrivaled diversity of morphologic traits and
breed-associated behaviors resulting from human selective pressures. To identify the …
breed-associated behaviors resulting from human selective pressures. To identify the …
Animal domestication in the era of ancient genomics
The domestication of animals led to a major shift in human subsistence patterns, from a
hunter–gatherer to a sedentary agricultural lifestyle, which ultimately resulted in the …
hunter–gatherer to a sedentary agricultural lifestyle, which ultimately resulted in the …
Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction
JA Robinson, J Räikkönen, LM Vucetich… - Science …, 2019 - science.org
The observation that small isolated populations often suffer reduced fitness from inbreeding
depression has guided conservation theory and practice for decades. However …
depression has guided conservation theory and practice for decades. However …
Runs of homozygosity: current knowledge and applications in livestock
E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
[HTML][HTML] Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture
Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …
[HTML][HTML] Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex
Human activity has caused dramatic population declines in many wild species. The resulting
bottlenecks have a profound impact on the genetic makeup of a species with unknown …
bottlenecks have a profound impact on the genetic makeup of a species with unknown …