The biological compositions including cells, proteins/peptides, nucleic acids, extracellular
vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and …

Great endeavors are undertaken to find effective nanoparticles to replace organic matrices
for the analysis of small molecules using laser desorption ionization mass spectrometry (LDI …

Sample pretreatment is an important prerequisite for analyzing complex samples due to the
low concentration of targets and numerous interferences in sample matrix. As a group of …

The flexible and controlled synthesis of metal–organic framework (MOF)-derived hybrid
nanostructures is of great significance in fine tuning of their enrichment performance in large …

Human health is always under global spotlight, but now it suffers from severe environmental
issue and various diseases. Developing highly selective and effective extraction technique …

Highly efficient extraction of phospho-and glycopeptides from complicated biological
samples is extremely crucial for comprehensive characterization of protein phosphorylation …

Here, silica microspheres were decorated with two-dimensional metal–organic frameworks
(2D MOFs) nanosheets and ionic liquids, and evaluated as the mixed-mode stationary …

Efficient adsorption/enrichment of protein species from complex biological matrixes is the
prerequisite in proteomic analysis. Metal–organic frameworks (MOFs) belong to an …

For a deep understanding of the human proteome, the first crucial step is always the
effective separation of targeted proteins/peptides from complex samples. In mass …

Metal–Organic Frameworks (MOFs) can deliver many advantages when acting as enzyme
mimics to assist with signal amplification in molecular detection: they have abundant active …