Phthalate metabolites: Characterization, toxicities, global distribution, and exposure assessment

YJ Zhang, JL Guo, J Xue, CL Bai, Y Guo - Environmental Pollution, 2021 - Elsevier
Phthalates are plasticizers in various products and regarded as endocrine disruptors due to
their anti-androgen effects. Environmental occurrence and toxicities of parent phthalates …

[HTML][HTML] The impact of Di-(2-ethylhexyl) Phthalate and Mono (2-ethylhexyl) Phthalate in placental development, function, and pathophysiology

LD Martínez-Razo, A Martínez-Ibarra… - Environment …, 2021 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a chemical widely distributed in the
environment as is extensively used in the plastic industry. DEHP is considered an endocrine …

Enhanced reproductive toxicities induced by phthalates contaminated microplastics in male mice (Mus musculus)

Y Deng, Z Yan, R Shen, Y Huang, H Ren… - Journal of Hazardous …, 2021 - Elsevier
It has been demonstrated that microplastics (MPs) can transport phthalate esters (PAEs) into
the tissues of mice. However, the influence of MPs on accumulation of PAEs and the …

Urinary phthalate metabolites and biomarkers of oxidative stress in pregnant women: a repeated measures analysis

KK Ferguson, TF McElrath, YH Chen… - Environmental …, 2015 - ehp.niehs.nih.gov
Background Phthalate exposure occurs readily in the environment and has been associated
with an array of health end points, including adverse birth outcomes. Some of these may be …

Oxidative stress induced by phthalates in mammals: state of the art and potential biomarkers

E Brassea-Pérez, CJ Hernández-Camacho… - Environmental …, 2022 - Elsevier
Background Phthalates, plasticizers that are widely used in consumer products including
toys, cosmetics, and food containers, have negative effects in liver, kidney, brain, lung and …

Variability in urinary phthalate metabolite levels across pregnancy and sensitive windows of exposure for the risk of preterm birth

KK Ferguson, TF McElrath, YA Ko, B Mukherjee… - Environment …, 2014 - Elsevier
Background Preterm birth is a significant public health problem, affecting over 1 in 10 live
births and contributing largely to infant mortality and morbidity. Everyday exposure to …

Urinary phthalate metabolite associations with biomarkers of inflammation and oxidative stress across pregnancy in Puerto Rico

KK Ferguson, DE Cantonwine… - … science & technology, 2014 - ACS Publications
Phthalate exposure during pregnancy has been linked to adverse birth outcomes such as
preterm birth, and inflammation and oxidative stress may mediate these relationships. In a …

A mechanism for the effect of endocrine disrupting chemicals on placentation

C Yang, G Song, W Lim - Chemosphere, 2019 - Elsevier
Numerous recent studies have shown that endocrine disrupting chemicals (EDCs) in the
body of pregnant women can pass through the placenta and be exposed to the fetus …

Mediation of the relationship between maternal phthalate exposure and preterm birth by oxidative stress with repeated measurements across pregnancy

KK Ferguson, YH Chen, TJ VanderWeele… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Mediation analysis is useful for understanding mechanisms and has been
used minimally in the study of the environment and disease. Objective: We examined …

[HTML][HTML] Maternal phthalate urine concentrations, fetal growth and adverse birth outcomes. A population-based prospective cohort study

S Santos, CM Sol, C van Zwol–Janssens… - Environment …, 2021 - Elsevier
Importance Exposure to phthalates may affect fetal growth, but previous studies are
inconsistent and have not explored the trimester-specific effects of phthalates on repeated …