There is robust epidemiological evidence for the beneficial effects of broccoli consumption
on health, many of them clearly mediated by the isothiocyanate sulforaphane. Present in the …

Significance: Sulforaphane, produced by the hydrolytic conversion of glucoraphanin after
ingestion of cruciferous vegetables, particularly broccoli and broccoli sprouts, has been …

Cardiovascular disease (CVD) causes an unparalleled proportion of the global burden of
disease and will remain the main cause of mortality for the near future. Oxidative stress plays …

In the last decade, most of the evidence on the clinical benefits of including cruciferous foods
in the diet has been focused on the content of glucosinolates (GSL) and their corresponding …

The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by NFE2L2) plays a
critical role in the maintenance of cellular redox and metabolic homeostasis, as well as the …

Relationships between diet and health have attracted attention for centuries; but links
between diet and cancer have been a focus only in recent decades. The consumption of diet …

Glucosinolates and their metabolites from Brassicaceae plants have received widespread
attention due to their anti-inflammatory effects. Glucosinolates occurs an “enterohepatic …

There is a growing interest in the health benefits of broccoli. Sulforaphane, the major
bioactive component in broccoli, is an unstable isothiocyanate stored in the plant as …

Tumorigenicity-inhibiting compounds have been identified in our daily diet. For example,
isothiocyanates (ITCs) found in cruciferous vegetables were reported to have potent cancer …

The benefits of the Mediterranean diet (MD) for protecting against chronic disorders such as
cardiovascular disease are usually attributed to high consumption of certain food groups …