The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

Chromones and coumarins are privileged scaffolds that are widely distributed in natural
products, synthetic building blocks, pharmaceutical agents, and functional materials …

A novel, practical and metal-free approach for the regioselective selenation of coumarins
employing (bis (trifluoroacetoxy) iodo) benzene (PIFA) at room temperature is presented …

Integration of viral DNA into the host chromosome is an essential step in the life cycle of
retroviruses and is facilitated by the viral integrase enzyme. The first generation of integrase …

HIV-1 integrase (IN) is the molecular target of the newly approved anti-AIDS drug raltegravir
(MK-0518, Isentress) while elvitegravir (GS-9137, JTK-303) is in clinical trials. The aims of …

Regioselective palladium -catalyzed olefination of coumarins via aerobic oxidative Heck
reactions - Chemical Communications (RSC Publishing) DOI:10.1039/C2CC37676H Royal …

HIV integrase (IN) catalyzes the insertion into the genome of the infected human cell of viral
DNA produced by the retrotranscription process. The discovery of raltegravir validated the …

The introduction of trifluoromethylthio groups into organic compounds, in particular
heterocycles, is important because of the prevalence of these structures in medicinally and …

Regioselective palladium -catalyzed direct cross-coupling of coumarins with simple arenes
- Chemical Communications (RSC Publishing) DOI:10.1039/C2CC34551J Royal Society of …

A practical and efficient synthesis of a complex chiral atropisomeric HIV integrase inhibitor
has been accomplished. The combination of a copper‐catalyzed acylation along with the …