The ability to adapt to altered availability of free water is a fundamental property of living
cells. The principles underlying osmoadaptation are well conserved. The yeast …

Microbial production of glycerol has been known for 150 years, and glycerol was produced
commercially during World War I. Glycerol production by microbial synthesis subsequently …

There is huge variability among yeasts with regard to their efficiency in utilizing glycerol as
the sole source of carbon and energy. Certain species show growth rates with glycerol …

Aquaporins (AQPs) are ubiquitous membrane proteins whose identification, pioneered by
Peter Agre's team in the early nineties, provided a molecular basis for transmembrane water …

Although sugars are clearly the preferred carbon sources of the yeast Saccharomyces
cerevisiae, nonfermentable substrates such as ethanol, glycerol, lactate, acetate or oleate …

We have characterized the strongly homologous GPP1/RHR2 and GPP2/HOR2 genes,
encoding isoforms of glycerol 3-phosphatase. Mutants lacking bothGPP1 and GPP2 are …

The Tor1p and Tor2p kinases, targets of the therapeutically important antibiotic rapamycin,
function as components of two distinct protein complexes in yeast, termed TOR complex 1 …

Several researchers have used crude glycerol as a source of substrate for methane
production and power generation, which is a way of adding value to this residue that has a …

Glycerol and other polyols are used as osmoprotectants by many organisms. Several yeasts
and other fungi can take up glycerol by proton symport. To identify genes involved in active …

The story of rapamycin is a pharmaceutical fairytale. Discovered as an antifungal activity in a
soil sample collected on Easter Island, this macrocyclic lactone and its derivatives are now …