Interactions between bacteriophage, bacteria, and the mammalian immune system

JD Van Belleghem, K Dąbrowska, M Vaneechoutte… - Viruses, 2018 - mdpi.com
The human body is host to large numbers of bacteriophages (phages)–a diverse group of
bacterial viruses that infect bacteria. Phage were previously regarded as bystanders that …

Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review

K Dąbrowska - Medicinal research reviews, 2019 - Wiley Online Library
Bacteriophages are not forgotten viruses anymore: scientists and practitioners seek to
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …

[图书][B] Bacteriophages: biology and applications

E Kutter, A Sulakvelidze - 2004 - taylorfrancis.com
In response to the emergence of pathogenic bacteria that cannot be treated with current
antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight …

Phage as a modulator of immune responses: practical implications for phage therapy

A Górski, R Międzybrodzki, J Borysowski… - Advances in virus …, 2012 - Elsevier
Although the natural hosts for bacteriophages are bacteria, a growing body of data shows
that phages can also interact with some populations of mammalian cells, especially with …

Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos

M Karimi, H Mirshekari, SMM Basri, S Bahrami… - Advanced drug delivery …, 2016 - Elsevier
The main goal of drug delivery systems is to target therapeutic cargoes to desired cells and
to ensure their efficient uptake. Recently a number of studies have focused on designing bio …

Pf bacteriophage and their impact on Pseudomonas virulence, mammalian immunity, and chronic infections

PR Secor, EB Burgener, M Kinnersley… - Frontiers in …, 2020 - frontiersin.org
Pf bacteriophage are temperate phages that infect the bacterium Pseudomonas aeruginosa,
a major cause of chronic lung infections in cystic fibrosis (CF) and other settings. Pf and …

Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells

TA Lehti, MI Pajunen, MS Skog, J Finne - Nature communications, 2017 - nature.com
Eukaryotic organisms are continuously exposed to bacteriophages, which are efficient gene
transfer agents in bacteria. However, bacteriophages are considered not to pass the …

Selective targeting of cancer cells using synthetic peptides

M Shadidi, M Sioud - Drug Resistance Updates, 2003 - Elsevier
To establish efficient and reliable therapeutic delivery into cancer cells, a number of delivery
agents and concepts have been investigated in the recent years. Among many …

Genetically engineered nanofiber-like viruses for tissue regenerating materials

A Merzlyak, S Indrakanti, SW Lee - Nano letters, 2009 - ACS Publications
Controlling structural organization and signaling motif display of biomimetic matrices at the
nanometer scale is of great importance to the functional design of tissue regenerating …

The enemy of my enemy: new insights regarding bacteriophage–mammalian cell interactions

K Bodner, AL Melkonian, MW Covert - Trends in Microbiology, 2021 - cell.com
Bacteriophages (phages) are the most abundant biological entity in the human body, but
until recently the role that phages play in human health was not well characterized. Although …