Molecular rotors: fluorescent sensors for microviscosity and conformation of biomolecules

M Paez‐Perez, MK Kuimova - Angewandte Chemie, 2024 - Wiley Online Library
The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …

Multiparametric single-vesicle flow cytometry resolves extracellular vesicle heterogeneity and reveals selective regulation of biogenesis and cargo distribution

AK von Lersner, F Fernandes, PMM Ozawa… - ACS …, 2024 - ACS Publications
Mammalian cells release a heterogeneous array of extracellular vesicles (EVs) that
contribute to intercellular communication by means of the cargo that they carry. To resolve …

[HTML][HTML] Lipid Rafts in Signalling, Diseases, and Infections: What Can Be Learned from Fluorescence Techniques?

S Anselmo, E Bonaccorso, C Gangemi, G Sancataldo… - Membranes, 2025 - mdpi.com
Lipid rafts are dynamic microdomains in the membrane, rich in cholesterol and
sphingolipids, that are critical for biological processes like cell signalling, membrane …

Fluorescent macrocycle-dye-anchor conjugates for sensing phospholipids in biomembranes

AS Oshchepkov, EC Da Silva, BS Morozov… - Sensors and Actuators B …, 2023 - Elsevier
Negatively charged phospholipids can serve as biomarkers for a number of biological
processes allowing detection of apoptosis in animal cells, drug-induced phospholipidosis as …

Enhanced Optical Biosensing by Aerotaxy Ga (as) P nanowire platforms suitable for scalable production

J Valderas-Gutiérrez, R Davtyan… - ACS Applied Nano …, 2022 - ACS Publications
Sensitive detection of low-abundance biomolecules is central for diagnostic applications.
Semiconductor nanowires can be designed to enhance the fluorescence signal from surface …

Specific Fluorescent Probes for Imaging DNA in Cell-Free Solution and in Mitochondria in Living Cells

AS Efimova, MA Ustimova, NS Chmelyuk… - Biosensors, 2023 - mdpi.com
New styryl dyes consisting of N-methylpyridine or N-methylquinoline scaffolds were
synthesized, and their binding affinities for DNA in cell-free solution were studied. The …

Flow Cytometry Analysis of Perturbations in the Bacterial Cell Envelope Enabled by Monitoring Generalized Polarization of the Solvatochromic Peptide UNR-1

L Weiss, D Bonnet, D Dziuba, J Karpenko - Analytical Chemistry, 2025 - ACS Publications
The worldwide spread of antibiotic resistance is considered to be one of the major health
threats to society. While developing new antibiotics is crucial, there is also a strong need for …

Modulation of Mechanosensitive Potassium Channels by a Membrane-targeted Nongenetic Photoswitch

M Moschetta, V Vurro, V Sesti, C Bertarelli… - The Journal of …, 2023 - ACS Publications
Mechanosensitive ion channels are present in the plasma membranes of all cells. They play
a fundamental role in converting mechanical stimuli into biochemical signals and are …

Membrane order effect on the photoresponse of an organic transducer

V Vurro, M Moschetta, G Bondelli, S Sardar, A Magni… - Membranes, 2023 - mdpi.com
Non-genetic photostimulation, which allows for control over cellular activity via the use of cell-
targeting phototransducers, is widely used nowadays to study and modulate/restore …

Polar ammoniostyryls easily converting a clickable lipophilic BODIPY in an advanced plasma membrane probe

S Serrano-Buitrago, M Muñoz-Úbeda… - Journal of Materials …, 2023 - pubs.rsc.org
A very simple, small and symmetric, but highly bright, photostable and functionalizable
molecular probe for plasma membrane (PM) has been developed from an accessible …