Recent developments in vascular imaging techniques in tissue engineering and regenerative medicine

PK Upputuri, K Sivasubramanian… - BioMed research …, 2015 - Wiley Online Library
Adequate vascularisation is key in determining the clinical outcome of stem cells and
engineered tissue in regenerative medicine. Numerous imaging modalities have been …

Can OCT angiography be made a quantitative blood measurement tool?

J Zhu, CW Merkle, MT Bernucci, SP Chong… - Applied sciences, 2017 - mdpi.com
Featured Application Optical Coherence Tomography Angiography (OCTA) is a technique
for label-free vascular imaging in fields such as ophthalmology, gastroenterology, cancer …

Neurophotonic tools for microscopic measurements and manipulation: status report

AS Abdelfattah, S Ahuja, T Akkin, SR Allu… - …, 2022 - spiedigitallibrary.org
Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …

Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography

SP Chong, CW Merkle, C Leahy… - Biomedical optics …, 2015 - opg.optica.org
Quantification of chromophore concentrations in reflectance mode remains a major
challenge for biomedical optics. Spectroscopic Optical Coherence Tomography (SOCT) …

Effect of electrical forepaw stimulation on capillary transit-time heterogeneity (CTH)

E Gutiérrez-Jiménez, C Cai… - Journal of Cerebral …, 2016 - journals.sagepub.com
Functional hyperemia reduces oxygen extraction efficacy unless counteracted by a
reduction of capillary transit-time heterogeneity of blood. We adapted a bolus tracking …

Deep learning toolbox for automated enhancement, segmentation, and graphing of cortical optical coherence tomography microangiograms

S Stefan, J Lee - Biomedical Optics Express, 2020 - opg.optica.org
Optical coherence tomography angiography (OCTA) is becoming increasingly popular for
neuroscientific study, but it remains challenging to objectively quantify angioarchitectural …

Laminar fMRI: What can the time domain tell us?

N Petridou, JCW Siero - Neuroimage, 2019 - Elsevier
The rapid developments in functional MRI (fMRI) acquisition methods and hardware
technologies in recent years, particularly at high field (≥ 7 T), have enabled unparalleled …

Baseline oxygen consumption decreases with cortical depth

P Mächler, N Fomin-Thunemann, M Thunemann… - PLoS …, 2022 - journals.plos.org
The cerebral cortex is organized in cortical layers that differ in their cellular density,
composition, and wiring. Cortical laminar architecture is also readily revealed by staining for …

Disturbances in the control of capillary flow in an aged APPswe/PS1ΔE9 model of Alzheimer's disease

E Gutiérrez-Jiménez, H Angleys, PM Rasmussen… - Neurobiology of …, 2018 - Elsevier
Vascular changes are thought to contribute to the development of Alzheimer's disease, and
both cerebral blood flow and its responses during neural activation are reduced before …

Scanning darkfield high-resolution microendoscope for label-free microvascular imaging

H Hou, Y Tang, JB Coole, A Kortum… - Biomedical Optics …, 2023 - opg.optica.org
Characterization of microvascular changes during neoplastic progression has the potential
to assist in discriminating precancer and early cancer from benign lesions. Here, we …