Discovery of Potent Multikinase Type-II Inhibitors Targeting CDK5 in the DFG-out Inactive State with Promising Potential against Glioblastoma

ZR Khan, PJ Welsby, I Stasik… - Journal of Medicinal …, 2024 - ACS Publications
Kinases have proven valuable targets in successful cancer drug discovery projects, but not
yet for malignant brain tumors where type-II inhibition of cyclin-dependent kinase 5 (CDK5) …

Synthesis and characterization of cis and trans cobalt (II) nalidixate complexes having a 1-(4-chlorophenyl)-3-(pyridin-4-ylmethyl) urea ligand

R Brahma, AP Singh, JB Baruah - Dalton Transactions, 2024 - pubs.rsc.org
The synthesis and characterization of specific cis-and trans-isomers of a cobalt (II) bis-
nalidixate complex with a pyridine-based urea, 1-(4-chlorophenyl)-3-(pyridin-4-ylmethyl) …