The effects of caloric restriction (CR) on the skeleton are well studied in adult rodents and
include lower cortical bone mass but higher trabecular bone volume. Much less is known …

Emerging evidence suggests that connexin mediated gap junctional intercellular
communication contributes to many aspects of bone biology including bone development …

We introduce a method for the analysis of multilocus, multitrait genetic data that provides an
intuitive and precise characterization of genetic architecture. We show that it is possible to …

Mechanical unloading induces muscle atrophy and bone loss; however, the time course and
interdependence of these effects is not well defined. We subjected 4‐month‐old C57BL/6J …

Abstract Connexin 43 (Cx43) is the most abundant gap junction protein in bone and has
been demonstrated as an integral component of skeletal homeostasis. In the present study …

Abstract Type 2 diabetes (T2D) incidence in adolescents is rising and may interfere with
peak bone mass acquisition. We tested the effects of early-onset T2D on bone mass …

Obesity is generally protective against osteoporosis and bone fracture. However, recent
studies indicate that the influence of obesity on the skeleton is complex and can be …

Introduction Since it is well documented that spatiotemporal gait parameters are affected by
body size, it is of limited clinical value to compare individual scores against reference values …

It is well known that estrogen deficiency induces a deterioration of bone strength in aged
females. The aim of this study is to determine the effect of estrogen depletion on tibia bone …

Dietary calcium (Ca) intake is needed to attain peak bone mineral density (BMD). Habitual
low Ca intake increases intestinal Ca absorption efficiency to protect bone mass, but the …