Benzothiazepines: Chemistry of a privileged scaffold

D Saha, G Jain, A Sharma - RSC advances, 2015 - pubs.rsc.org
Benzothiazepines are one such class of heterocyclic scaffolds with celebrated biological
activities. The flooding of the pharmaceutical market with cardiovascular drugs like diltiazem …

The 3, 4-dioxygenated 5-hydroxy-4-aryl-quinolin-2 (1 H)-one alkaloids. Results of 20 years of research, uncovering a new family of natural products

SO Simonetti, EL Larghi, TS Kaufman - Natural product reports, 2016 - pubs.rsc.org
Covering: up to April 2016 Aspergillus and Penicillium are fungal species known to produce
a high diversity of secondary metabolites, many of them endowed with interesting bioactivity …

Insight view on possible role of fluoroquinolones in cancer therapy

PC Sharma, M Chaudhary, A Sharma… - Current topics in …, 2013 - ingentaconnect.com
Cancer is a disease without limits turning out to be prime cause for raising death toll around
the world. Several treatment strategies including chemotherapy, surgery and radiotherapy …

A convenient approach to an advanced intermediate toward the naturally occurring, bioactive 6-substituted 5-hydroxy-4-aryl-1 H-quinolin-2-ones

SO Simonetti, EL Larghi, TS Kaufman - Organic & Biomolecular …, 2016 - pubs.rsc.org
5-Hydroxy-4-aryl-3, 4-dihydro-1H-quinolin-2-ones are a small family of natural products
isolated from fungal strains of Penicillium and Aspergillus. Most of its members, which are …

Synthesis, reactions, and biological activity of 1, 4-thiazepines and their fused aryl and heteroaryl derivatives: a review

KAM El-Bayouki - Journal of Sulfur Chemistry, 2011 - Taylor & Francis
Full article: Synthesis, reactions, and biological activity of 1,4-thiazepines and their fused aryl
and heteroaryl derivatives: a review Skip to Main Content Taylor and Francis Online homepage …

Thiophene ring-opening reactions. Direct access to the synthesis of 1, 3, 4-thiadiazoline-(condenced) pyridone hybrids

MM Abadleh, AH Abdullah, FF Awwadi… - Tetrahedron, 2021 - Elsevier
The reaction of N'-(aryl) benzothiohydrazides with 2-chloro-7-cyclopropyl-3-nitro-4-
oxothieno [2, 3-b] pyridine-5-carboxylic ester/acid in the presence of triethylamine furnished …

Synthesis and antimicrobial activity of 2,4-diaryl-2,3-dihydrobenzo[b][1,4]thiazepines

M Kumar, K Sharma, AK Fogla, K Sharma… - Research on Chemical …, 2013 - Springer
A new series of structurally diverse 2, 3-dihydrobenzo [b][1, 4] thiazepines (2, 3-dihydro-1, 5-
benzothiazepines) with substituted phenyl groups at C (2) and C (4) have been synthesized …

One Pot Regioselective Synthesis of a Small Library of Dibenzo[b,f][1,4]thiazepin-11(10H)-ones via Smiles Rearrangement

Y Zhao, Q Dai, Z Chen, Q Zhang, Y Bai… - ACS Combinatorial …, 2013 - ACS Publications
A facile and efficient method has been developed for the synthesis of a small library of
dibenzo [b, f][1, 4] thiazepin-11 (10 H)-ones via Smiles rearrangement. Compounds were …

Solvent-free and self-catalyzed three-component synthesis of diversely substituted pyrazolo [1, 4] thiazepinones of potential antitumor activity

R Abonia - Current Organic Synthesis, 2014 - ingentaconnect.com
In this work we report the highly efficient solvent-free and self-catalyzed three-component
approach for the synthesis of pyrazolo [3, 4-e][1, 4] thiazepin-7 (4H)-ones. The reaction …

Heterocycles [h]-fused onto 4-oxoquinoline-3-carboxylic acid. Part XII: synthesis of 5-fluoro-7-oxodihydo[1,3,4]thiadiazino [5,6-h]quinoline-8-carboxylic acid and ester

MM El-Abadelah, MM Abadleh, FF Awwadi… - … für Naturforschung B, 2018 - degruyter.com
Direct interaction of dithizone with 7-chloro-6-fluoro-8-nitro-4-oxoquinoline-3-carboxylic acid
or with its ester delivered the corresponding novel 1, 3, 4-thiadiazino [5, 6-h] quinoline 3 …