Fungi are abundant in the environment, causing our lungs to be constantly exposed to a
diverse range of species. While the majority of these are cleared effectively in healthy …

Aspergillus fumigatus, an opportunistic human pathogen, frequently infects the lungs of
people with cystic fibrosis and is one of the most common causes of infectious-disease …

In this review, we summarize and briefly discuss various approaches to modeling the
metabolism in human immune cells, with a focus on energy metabolism. These approaches …

In the field of lipid research, bioorthogonal chemistry has made the study of lipid uptake and
processing in living systems possible, whilst minimising biological properties arising from …

The ability to overcome metabolic stress is a major determinant of outcomes during
infections. Pathogens face nutrient and oxygen deprivation in host niches and during their …

A viral infection involves entry and replication of viral nucleic acid in a host organism,
subsequently leading to biochemical and structural alterations in the host cell. In the case of …

Purpose: The purpose of this study was to explore the role of thymic stromal lymphopoietin
(TSLP) secreted by Aspergillus fumigatus–stimulated dendritic cells (DCs) during the T …

Fungi are diverse organisms with various characteristics and functions. Some play a role in
recycling essential elements, such as nitrogen and carbon, while others are utilized in the …

Respiratory specimens obtained from patients with chronic forms of aspergillosis contain
phenotypic variants of azole-resistant Aspergillus fumigatus (ARAF) that co-exist in the …

Metabolomics has emerged as a transformative tool in the study of microbes, including
pathogenic fungi, facilitating the identification of unique metabolic profiles that elucidate their …