The contemporary scientific community has presently recognized flavonoids to be a unique
class of therapeutic molecules due to their diverse therapeutic properties. Of these, rutin …

The common and persistent failures to translate promising preclinical drug candidates into
clinical success highlight the limited effectiveness of disease models currently used in drug …

To overcome the recent outbreaks of hepatotoxicity-related drugs, a new analytical tool for
the continuously determination of these drugs in human fluids is required. Electrochemical …

Background Hepatology research has focused on developing traditional therapies as
pharmacological medicines to treat liver cirrhosis. Thus, this study evaluated mechanisms of …

The liver is the largest, important organ and the site for essential biochemical reactions in
the human body. It has the function to detoxify toxic substances and synthesize useful …

Computed tomography (CT) imaging remains the most utilized modality for liver-related
cancer screening and treatment monitoring purposes. Liver, liver tumor and liver vasculature …

The purpose of this study was to determine the effects of single and combined
administrations of deoxynivalenol (DON) and zearalenone (ZEN) on the histology and …

Drug-induced liver injury is the most common cause of market withdrawal of
pharmaceuticals, and thus, there is considerable need for better prediction models for DILI …

Relations between hyperlipidemia and chronic pancreatitis remain unclear. Microcirculatory
disturbances and oxidative stress are involved in pathogeneses of a high numbers of …

Background Drug‐induced liver injury (DILI) is the most common reason for a drug to be
withdrawn from the market. Apart from stopping the offending drug, no regimens are …