Chronic pain is a maladaptive neurological disease that remains a major health problem. A
deepening of our knowledge on mechanisms that cause pain is a prerequisite to developing …

The function of normal and defective candidate genes for human genetic diseases, which
are rapidly being identified in large numbers by human geneticists and the biomedical …

Abstract Xenbase (https://www. xenbase. org/), the Xenopus model organism
knowledgebase, is a web-accessible resource that integrates the diverse genomic and …

Limb regeneration is a frontier in biomedical science. Identifying triggers of innate
morphogenetic responses in vivo to induce the growth of healthy patterned tissue would …

Precision medicine promises to dramatically improve patient outcomes and reduce health
care costs through a shift in focus from disease treatment to prevention and individualized …

At a fundamental level most genes, signaling pathways, biological functions and organ
systems are highly conserved between man and all vertebrate species. Leveraging this …

From its long history in the field of embryology to its recent advances in genetics, Xenopus
has been an indispensable model for understanding the human brain. Foundational studies …

Delorazepam, a derivative of diazepam, is a psychotropic drug belonging to the
benzodiazepine class. Used as a nervous-system inhibitor, it treats anxiety, insomnia, and …

Xenopus laevis is a classic developmental model, but its allotetraploid genome has limited
our ability to perform genetic manipulations. The advance of... Studying genes involved in …

The global rate of wildlife extinctions is accelerating, and the persistence of many species
requires conservation breeding programs. A central paradigm of these programs is to …