Cancer is one of the most common causes of death. So, its lethal effect increases with time.
Near about hundreds of cancers are known in humans. Cancer treatment is done to cure or …

Proteolysis-targeting chimera (PROTAC) technology represents a novel and promising
modality for targeted protein degradation with transformative implications for the clinical …

We report here a tumor‐pretargted theranostic approach for multimodality imaging‐guided
synergistic cancer PDT by cascade alkaline phosphatase (ALP)‐mediated in situ self …

Proteolysis-targeting chimera (PROTAC) is emerging as a new strategy to degrade target
proteins in a precise way by taking advantage of the cellular ubiquitin-proteasome system …

Triple-negative breast cancer (TNBC) is one of the deadliest subtypes of breast cancer (BC)
for its high aggressiveness, heterogeneity, and hypoxic nature. Based on biological and …

Over the past two decades, bioorthogonal chemistry has undergone a remarkable
development, challenging traditional assumptions in biology and medicine. Recent …

Targeted protein degradation (TPD) has emerged as a revolutionary paradigm in drug
discovery and development, offering a promising avenue to tackle challenging therapeutic …

Proteolysis-targeting chimeras (PROTACs) technology has garnered significant attention
over the last 10 years, representing a burgeoning therapeutic approach with the potential to …

Abstract Proteolysis Targeting Chimeras (PROTACs) represent a significant advancement in
therapeutic drug development by leveraging the ubiquitin‐proteasome system to enable …

Oral delivery of probiotics has been a promising method for treatment of inflammatory bowel
diseases (IBDs). However, probiotics always suffer from substantial loss of viability due to …