Preclinical research of stem cells: challenges and progress

J Li, Y Wu, X Yao, Y Tian, X Sun, Z Liu, X Ye… - Stem Cell Reviews and …, 2023 - Springer
In recent years, great breakthroughs have been made in basic research and clinical
applications of stem cells in regenerative medicine and other fields, which continue to …

Current Researches in Modular Biofabrication: Tissue Building Blocks and Bioreactors

S Zakhireh, A Mesgari-Shadi, J Barar, Y Omidi… - Korean Journal of …, 2024 - Springer
Modular tissue engineering (TE) is based on the design, fabrication, and arrangement of
replicated microtissue constructs to generate functional tissues. The advantage of this …

Computational modeling and experimental characterization of fluid dynamics in micro-CT scanned scaffolds within a multiple-sample airlift perfusion bioreactor

E Capuana, S Campora, G Catanzaro… - Biochemical …, 2023 - Elsevier
The perfusion of flow during cell culture induces cell proliferation and enhances cellular
activity. Perfusion bioreactors offer a controlled dynamic environment for reliable in vitro …

Three‐dimensional (3D) polylactic acid gradient scaffold to study the behavior of osteosarcoma cells under dynamic conditions

A De Luca, E Capuana, C Carbone… - … Research Part A, 2024 - Wiley Online Library
This study adopts an in vitro method to recapitulate the behavior of Saos‐2 cells, using a
system composed of a perfusion bioreactor and poly‐L‐lactic acid (PLLA) scaffold fabricated …

Advances in modeling analysis for multi-parameter bioreactor process control

X Lin, K Li, C Wu, C Zhang, G Zhang, X Huo - … and Bioprocess Engineering, 2025 - Springer
The multi-parameter intricate process control of bioreactor systems poses an urgent
challenge to cell culture. It is feasible to simulate and analyze the implications of each …

Design and optimization of 3D-bioprinted cell-laden scaffolds in dynamic culture

J Li, F Chen, M Wang, X Zhu, N He, N Li… - … Journal of Bioprinting, 2024 - accscience.com
Light-based 3D printing enables the fabrication of biological scaffolds with high precision,
versatility and biocompatibility, particularly the cell-laden scaffolds with architecturally …

The development of the multi-physical model for cell-laden nerve scaffolds and its bioprinting by stereolithography

J Li, N He, F Chen, X Han - Materials Today: Proceedings, 2022 - Elsevier
Abstract 3D bioprinting is a novel manufacturing technology that can directly stack
biocompatible materials mixed with cells layer by layer to form parts, enabling complex …

An Airlift Perfusion Bioreactor for Tissue Engineering Applications: from Computational Modeling to Experimental Validation

E Capuana, C Carbone, FC Pavia, G Ghersi… - Chemical Engineering …, 2024 - cetjournal.it
Tissue engineering (TE) offers promising solutions for regenerative medicine through the
use of porous scaffolds and cells, providing a favorable environment for the production of …