[PDF][PDF] Genetic modifiers of sickle cell disease
Studies of genetic variants and their associations with disease outcomes using recent
molecular technology advances and the broad variety of statistical methodologies available …
molecular technology advances and the broad variety of statistical methodologies available …
Genetic variation and sickle cell disease severity: a systematic review and meta-analysis
Importance Sickle cell disease (SCD) is a monogenic disorder, yet clinical outcomes are
influenced by additional genetic factors. Despite decades of research, the genetics of SCD …
influenced by additional genetic factors. Despite decades of research, the genetics of SCD …
Reviewing and assessing existing meta-analysis models and tools
FL Makinde, MSS Tchamga, J Jafali… - Briefings in …, 2021 - academic.oup.com
Over the past few years, meta-analysis has become popular among biomedical researchers
for detecting biomarkers across multiple cohort studies with increased predictive power …
for detecting biomarkers across multiple cohort studies with increased predictive power …
Systematic Review of Genetic Modifiers Associated with the Development and/or Progression of Nephropathy in Patients with Sickle Cell Disease
V Labarque, EC Okocha - International Journal of Molecular Sciences, 2024 - mdpi.com
Sickle cell nephropathy (SCN) is a common complication of sickle cell disease (SCD) that
significantly contributes to morbidity and mortality. In addition to clinical and life-style factors …
significantly contributes to morbidity and mortality. In addition to clinical and life-style factors …
APOBEC-1 Complementation Factor: From RNA Binding to Cancer
L Wang, Q Cheng - Cancer Control, 2024 - journals.sagepub.com
Background APOBEC-1 complementation factor (A1CF) and Apolipoprotein B mRNA editing
enzyme, catalytic polypeptide-1 (APOBEC-1) constitute the minimal proteins necessary for …
enzyme, catalytic polypeptide-1 (APOBEC-1) constitute the minimal proteins necessary for …
Association of Normal and Mutated APOL1 G2 Rs60910145 alleles with SCD, Body Mass Index, and Renal Function Biomarkers and Indices
Purpose of the study: The current study aimed to detect the frequency of normal and mutated
APOL1 alleles in sickle cell disease (SCD) patients and test their relation with …
APOL1 alleles in sickle cell disease (SCD) patients and test their relation with …
Déterminants génétiques constitutionnels et acquis de la sévérité de l'anémie falciforme: études de l'impact des variants germinaux sur les traits sanguins et de l' …
T Pincez - 2024 - papyrus.bib.umontreal.ca
L'anémie falciforme (AF) est une maladie monogénique dans laquelle la polymérisation
d'une hémoglobine anormale (hémoglobine S, Hb S) entraine la déformation et la …
d'une hémoglobine anormale (hémoglobine S, Hb S) entraine la déformation et la …
Análise multifatorial dos moduladores da gravidade da anemia falciforme ea exploração racional dos parâmetros na estratificação do perfil fenotípico como …
II Wilke - 2021 - lume.ufrgs.br
A anemia falciforme (AF) é hoje a doença genética mais prevalente mundialmente,
caracterizada por um alto índice de morbimortalidade e considerada como a mais grave …
caracterizada por um alto índice de morbimortalidade e considerada como a mais grave …