Young-onset type 2 diabetes mellitus—Implications for morbidity and mortality

DJ Magliano, JW Sacre, JL Harding… - Nature Reviews …, 2020 - nature.com
Accumulating data suggest that type 2 diabetes mellitus (T2DM) in younger people (aged<
40 years), referred to as young-onset T2DM, has a more rapid deterioration of β-cell function …

ISPAD Clinical Practice Consensus Guidelines 2022: Type 2 diabetes in children and adolescents

AS Shah, PS Zeitler, J Wong, AS Pena… - Pediatric …, 2022 - Wiley Online Library
Since the 2018 ISPAD guidelines on this topic, follow‐up of large cohorts from around the
globe have continued informing the current incidence and prevalence of co‐morbidities and …

Worldwide estimates of incidence of type 2 diabetes in children and adolescents in 2021

H Wu, CC Patterson, X Zhang, RBA Ghani… - Diabetes research and …, 2022 - Elsevier
Aims We aimed to conduct a systematic review of published studies on the incidence of type
2 diabetes in children and adolescents aged under 20 years and provide worldwide …

The epidemiology, molecular pathogenesis, diagnosis, and treatment of maturity-onset diabetes of the young (MODY)

KM Nkonge, DK Nkonge, TN Nkonge - Clinical Diabetes and …, 2020 - Springer
Background The most common type of monogenic diabetes is maturity-onset diabetes of the
young (MODY), a clinically and genetically heterogeneous group of endocrine disorders that …

Childhood obesity: causes, consequences, and management

M Gurnani, C Birken, J Hamilton - Pediatric Clinics, 2015 - pediatric.theclinics.com
Childhood Obesity - Pediatric Clinics Skip to Main Content Pediatric Clinics Log in Register
Log in Subscribe Claim Skip menu theclinics.com theclinics.com External Link All Clinics …

The prevalence of obesity among children with type 2 diabetes: a systematic review and meta-analysis

M Cioana, J Deng, A Nadarajah, M Hou… - JAMA Network …, 2022 - jamanetwork.com
Importance The childhood obesity epidemic is presumed to drive pediatric type 2 diabetes
(T2D); however, the global scale of obesity in children with T2D is unknown. Objectives To …

Diabetes in the young–a global view and worldwide estimates of numbers of children with type 1 diabetes

C Patterson, L Guariguata, G Dahlquist… - Diabetes research and …, 2014 - Elsevier
This paper describes the methodology, results and limitations of the 2013 International
Diabetes Federation (IDF) Atlas (6th edition) estimates of the worldwide numbers of …

Youth-onset type 2 diabetes mellitus: an urgent challenge

P Bjornstad, LC Chao, M Cree-Green, AB Dart… - Nature Reviews …, 2023 - nature.com
The incidence and prevalence of youth-onset type 2 diabetes mellitus (T2DM) and its
complications are increasing worldwide. Youth-onset T2DM has been reported in all racial …

Systematic population screening, using biomarkers and genetic testing, identifies 2.5% of the UK pediatric diabetes population with monogenic diabetes

M Shepherd, B Shields, S Hammersley… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Monogenic diabetes is rare but is an important diagnosis in pediatric diabetes
clinics. These patients are often not identified as this relies on the recognition of key clinical …

Biological, environmental, and social influences on childhood obesity

MK Campbell - Pediatric research, 2016 - nature.com
The prevalence of childhood obesity has increased globally over the past three decades,
with evidence of recent leveling off in developed countries. Reduction in the, currently high …