[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery

K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

[HTML][HTML] Ultrasound and microbubbles to beat barriers in tumors: Improving delivery of nanomedicine

S Snipstad, K Vikedal, M Maardalen… - Advanced Drug Delivery …, 2021 - Elsevier
Successful delivery of drugs and nanomedicine to tumors requires a functional vascular
network, extravasation across the capillary wall, penetration through the extracellular matrix …

The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation

S Roovers, T Segers, G Lajoinie, J Deprez, M Versluis… - Langmuir, 2019 - ACS Publications
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Advances in the mechanism of different antibacterial strategies based on ultrasound technique for controlling bacterial contamination in food industry

J Dai, M Bai, C Li, H Cui, L Lin - Trends in Food Science & Technology, 2020 - Elsevier
Background Pathogenic bacteria contamination has been a global health challenge in the
food industry. In this context, ultrasound technique is attracting much more attention as an …

Acoustic behavior of microbubbles and implications for drug delivery

K Kooiman, HJ Vos, M Versluis, N De Jong - Advanced drug delivery …, 2014 - Elsevier
Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they
increasingly show potential for drug delivery. This review focuses on the acoustic behavior …

Ultrasound nanotheranostics: Toward precision medicine

Y Qin, X Geng, Y Sun, Y Zhao, W Chai, X Wang… - Journal of Controlled …, 2023 - Elsevier
Ultrasound (US) is a mechanical wave that can penetrate biological tissues and trigger
complex bioeffects. The mechanisms of US in different diagnosis and treatment are different …

Applications of focused ultrasound for the treatment of glioblastoma: a new frontier

AM Hersh, M Bhimreddy, C Weber-Levine, K Jiang… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma (GBM) is a common primary brain tumor with a short median
overall survival despite aggressive treatment with resection, chemotherapy, and radiation …

[HTML][HTML] Mechanisms underlying sonoporation: Interaction between microbubbles and cells

Y Yang, Q Li, X Guo, J Tu, D Zhang - Ultrasonics Sonochemistry, 2020 - Elsevier
The past several decades have witnessed great progress in “smart drug delivery”, an
advance technology that can deliver genes or drugs into specific locations of patients' body …

Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis

I De Cock, E Zagato, K Braeckmans, Y Luan… - Journal of controlled …, 2015 - Elsevier
Although promising results are achieved in ultrasound mediated drug delivery, its underlying
biophysical mechanisms remain to be elucidated. Pore formation as well as endocytosis has …