Stimuli-responsive therapeutic metallodrugs

X Wang, X Wang, S Jin, N Muhammad, Z Guo - Chemical reviews, 2018 - ACS Publications
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

Rational design of cancer nanomedicine: nanoproperty integration and synchronization

Q Sun, Z Zhou, N Qiu, Y Shen - Advanced materials, 2017 - Wiley Online Library
Current cancer nanomedicines can only mitigate adverse effects but fail to enhance
therapeutic efficacies of anticancer drugs. Rational design of next‐generation cancer …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J Xiang, N Qiu, Y Wang, Y Piao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

[HTML][HTML] Copper-mediated living radical polymerization (atom transfer radical polymerization and copper (0) mediated polymerization): from fundamentals to …

C Boyer, NA Corrigan, K Jung, D Nguyen… - Chemical …, 2016 - ACS Publications
The discovery of the first “living” radical polymerization by Otsu and co-workers (1) in 1982
heralded the start of a very exciting time for polymer chemists. Since then, a plethora of living …

Carbon nanotubes for delivery of small molecule drugs

BS Wong, SL Yoong, A Jagusiak, T Panczyk… - Advanced drug delivery …, 2013 - Elsevier
In the realm of drug delivery, carbon nanotubes (CNTs) have gained tremendous attention
as promising nanocarriers, owing to their distinct characteristics, such as high surface area …

Targeting and delivery of platinum-based anticancer drugs

X Wang, Z Guo - Chemical Society Reviews, 2013 - pubs.rsc.org
Platinum-based anticancer drugs occupy a crucial role in the treatment of various malignant
tumours. However, the efficacy and applicability of platinum drugs are heavily restricted by …

Nanocarriers for delivery of platinum anticancer drugs

HS Oberoi, NV Nukolova, AV Kabanov… - Advanced drug delivery …, 2013 - Elsevier
Platinum based anticancer drugs have revolutionized cancer chemotherapy, and continue to
be in widespread clinical use especially for management of tumors of the ovary, testes, and …

Nanopreparations to overcome multidrug resistance in cancer

NR Patel, BS Pattni, AH Abouzeid… - Advanced drug delivery …, 2013 - Elsevier
Multidrug resistance is the most widely exploited phenomenon by which cancer eludes
chemotherapy. Broad variety of factors, ranging from the cellular ones, such as over …

pH-Responsive polymers: synthesis, properties and applications

S Dai, P Ravi, KC Tam - Soft Matter, 2008 - pubs.rsc.org
pH-Responsive polymers are systems whose solubility, volume, and chain conformation can
be manipulated by changes in pH, co-solvent, and electrolytes. This review summarizes …

Carbon nanotubes as cancer therapeutic carriers and mediators

KH Son, JH Hong, JW Lee - International journal of nanomedicine, 2016 - Taylor & Francis
Carbon nanotubes (CNTs) have received increasing attention in biomedical fields because
of their unique structures and properties, including high aspect ratios, large surface areas …