Immunology of acute and chronic wound healing

K Raziyeva, Y Kim, Z Zharkinbekov, K Kassymbek… - Biomolecules, 2021 - mdpi.com
Skin wounds greatly affect the global healthcare system, creating a substantial burden on
the economy and society. Moreover, the situation is exacerbated by low healing rates, which …

The role of the extracellular matrix (ECM) in wound healing: a review

RB Diller, AJ Tabor - Biomimetics, 2022 - mdpi.com
The extracellular matrix (ECM) is a 3-dimensional structure and an essential component in
all human tissues. It is comprised of varying proteins, including collagens, elastin, and …

Skin wound healing: normal macrophage function and macrophage dysfunction in diabetic wounds

SM Aitcheson, FD Frentiu, SE Hurn, K Edwards… - Molecules, 2021 - mdpi.com
Macrophages play a prominent role in wound healing. In the early stages, they promote
inflammation and remove pathogens, wound debris, and cells that have apoptosed. Later in …

[HTML][HTML] VEGF/VEGFR-targeted therapy and immunotherapy in non-small cell lung cancer: targeting the tumor microenvironment

Y Zhao, S Guo, J Deng, J Shen, F Du… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is the leading cause of death by cancer worldwide.
Despite developments in therapeutic approaches for the past few decades, the 5-year …

Encoded structural color microneedle patches for multiple screening of wound small molecules

M Lu, X Zhang, D Xu, N Li, Y Zhao - Advanced Materials, 2023 - Wiley Online Library
Detection of biomarkers associated with wound conditions provides in‐depth healthcare
information and benefits wound healing treatment. The current aim of wound detection is to …

Cellular and molecular mechanisms of skin wound healing

OA Peña, P Martin - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

The roles of inflammation in keloid and hypertrophic scars

ZC Wang, WY Zhao, Y Cao, YQ Liu, Q Sun… - Frontiers in …, 2020 - frontiersin.org
The underlying mechanisms of wound healing are complex but inflammation is one of the
determining factors. Besides its traditional role in combating against infection upon injury …

Pathophysiology of Post-COVID syndromes: a new perspective

GES Batiha, HM Al-Kuraishy, AI Al-Gareeb, NN Welson - Virology Journal, 2022 - Springer
Most COVID-19 patients recovered with low mortality; however, some patients experienced
long-term symptoms described as “long-COVID” or “Post-COVID syndrome”(PCS). Patients …

Myofibroblasts: function, formation, and scope of molecular therapies for skin fibrosis

Y Tai, EL Woods, J Dally, D Kong, R Steadman… - Biomolecules, 2021 - mdpi.com
Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in
pathophysiological processes. Myofibroblasts mediate wound contractions, but their …

Why traditional herbal medicine promotes wound healing: Research from immune response, wound microbiome to controlled delivery

Z Xu, M Dong, S Yin, J Dong, M Zhang, R Tian… - Advanced Drug Delivery …, 2023 - Elsevier
Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …