Metabolic anomalies contribute to tissue dysfunction. Current metabolism research spans
from organelles to populations, and new technologies can accommodate investigation …

Protein film electrochemistry (PFE) has given unrivalled insight into the properties of redox
proteins and many electron-transferring enzymes, allowing investigations of otherwise ill …

A subgroup of patients infected with SARS-CoV-2 remain symptomatic over three months
after infection. A distinctive symptom of patients with long COVID is post-exertional malaise …

Ferroptosis is a form of regulated cell death with roles in degenerative diseases and cancer.
Excessive iron-catalyzed peroxidation of membrane phospholipids, especially those …

Glucose, the primary cellular energy source, is metabolized through glycolysis initiated by
the rate-limiting enzyme hexokinase (HK). In energy-demanding tissues like the brain, HK1 …

Purinosomes serve as metabolons to enhance de novo purine synthesis (DNPS) efficiency
through compartmentalizing DNPS enzymes during stressed conditions. However, the …

Steady state erythropoiesis produces new erythrocytes at a constant rate to replace the
senescent cells that are removed by macrophages in the liver and spleen. However …

De novo l‐serine biosynthesis in the mammalian astrocytes proceeds via a linear, three‐
step pathway (the phosphorylated pathway) catalysed by 3‐phosphoglycerate …

Fluctuations in nutrient and biomass availability, often as a result of disease, impart
metabolic challenges that must be overcome in order to sustain cell survival and promote …

Intricate coupling between metabolism and protein post-translational modifications (PTMs)
has emerged as a fundamental aspect of cellular regulation. Recent studies demonstrate …