Binding of arrestin to phosphorylated G-protein-coupled receptors (GPCRs) controls many
aspects of cell signaling. The number and arrangement of phosphates may vary …

Herein the development of cellular impedance biosensors, electrochemical impedance
spectroscopy, and the general principles and terms associated with the cell–electrode …

Histamine is a pleiotropic mediator involved in a broad spectrum of (patho)-physiological
processes, one of which is the regulation of inflammation. Compounds acting on three out of …

Background: The atypical chemokine receptor 3 (ACKR3) belongs to the superfamily of G
protein-coupled receptors (GPCRs). Unlike classical GPCRs, this receptor does not activate …

Class AG protein‐coupled receptors (GPCRs) continue to garner interest for their essential
roles in cell signalling and their importance as drug targets. Although numerous drugs in the …

More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that
play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling …

The histamine H1 receptor (H1R) is a G protein-coupled receptor (GPCR) and plays a key
role in allergic reactions upon activation by histamine which is locally released from mast …

Alzheimer's disease (AD) represents the principal cause of dementia among the elderly.
Great efforts have been established to understand the physiopathology of AD. Changes in …

G protein-coupled receptors (GPCRs) are currently appreciated to be routed to diverse
cellular platforms to generate both G protein-dependent and-independent signals. The latter …

Abstract GPR27, GPR85 and GPR173 constitute a small family of G protein-coupled
receptors (GPCR) that share the distinctive characteristics of being highly conserved …