Explaining dopamine through prediction errors and beyond

SJ Gershman, JA Assad, SR Datta, SW Linderman… - Nature …, 2024 - nature.com
The most influential account of phasic dopamine holds that it reports reward prediction
errors (RPEs). The RPE-based interpretation of dopamine signaling is, in its original form …

Spontaneous behaviour is structured by reinforcement without explicit reward

JE Markowitz, WF Gillis, M Jay, J Wood, RW Harris… - Nature, 2023 - nature.com
Spontaneous animal behaviour is built from action modules that are concatenated by the
brain into sequences,. However, the neural mechanisms that guide the composition of …

A feature-specific prediction error model explains dopaminergic heterogeneity

RS Lee, Y Sagiv, B Engelhard, IB Witten… - Nature neuroscience, 2024 - nature.com
The hypothesis that midbrain dopamine (DA) neurons broadcast a reward prediction error
(RPE) is among the great successes of computational neuroscience. However, recent …

Action prediction error: a value-free dopaminergic teaching signal that drives stable learning

F Greenstreet, HM Vergara, Y Johansson, S Pati… - BiorXiv, 2022 - biorxiv.org
Animals' choice behavior is characterized by two main tendencies: taking actions that led to
rewards and repeating past actions. Theory suggests these strategies may be reinforced by …

The role of motor cortex in motor sequence execution depends on demands for flexibility

KGC Mizes, J Lindsey, GS Escola, BP Ölveczky - Nature Neuroscience, 2024 - nature.com
The role of the motor cortex in executing motor sequences is widely debated, with studies
supporting disparate views. Here we probe the degree to which the motor cortex's …

Predictive auxiliary objectives in deep RL mimic learning in the brain

C Fang, KL Stachenfeld - arXiv preprint arXiv:2310.06089, 2023 - arxiv.org
The ability to predict upcoming events has been hypothesized to comprise a key aspect of
natural and machine cognition. This is supported by trends in deep reinforcement learning …

[HTML][HTML] Motor cortex is required for flexible but not automatic motor sequences

KGC Mizes, J Lindsey, GS Escola, BP Ölveczky - bioRxiv, 2023 - ncbi.nlm.nih.gov
How motor cortex contributes to motor sequence execution is much debated, with studies
supporting disparate views. Here we probe the degree to which motor cortex's engagement …

Dynamics of striatal action selection and reinforcement learning

J Lindsey, JE Markowitz, WF Gillis, SR Datta… - …, 2024 - pmc.ncbi.nlm.nih.gov
Spiny projection neurons (SPNs) in dorsal striatum are often proposed as a locus of
reinforcement learning in the basal ganglia. Here, we identify and resolve a fundamental …

[PDF][PDF] Reinforcement learning with dopamine: a convergence of natural and artificial intelligence

P Masset, SJ Gershman - The Handbook of Dopamine. Elsevier, 2024 - gershmanlab.com
Reinforcement learning is the problem of predicting and maximizing long-term reward.
Computer scientists recognized that this problem could be solved by updating predictions …

A computational principle of habit formation

KJ Lakshminarasimhan - bioRxiv, 2024 - biorxiv.org
Actions are influenced by multiple decision-making systems--including a goal-directed
system that favors rewarded actions and a habit system that repeats past actions--but …